| 史琦玉,王磊,张金宝.窄带双变焦放大内镜对胃部癌前病变及早期胃癌的诊断价值[J].安徽医药,2023,27(1):103-107. |
| 窄带双变焦放大内镜对胃部癌前病变及早期胃癌的诊断价值 |
| Application value of narrowband double zoom magnifying endoscopy in the differentiation degree of gastric precancerous lesions and early gastric cancer |
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| DOI：10.3969/j.issn.1009-6469.2023.01.023 |
| 中文关键词: 胃镜检查 胃肿瘤 癌前状态 放大器，电子 癌症早期检测 窄带双变焦放大内镜 活检 |
| 英文关键词: Gastroscopy Stomach neoplasms Precancerous conditions Amplifiers,electronic Early detection of cancer Dual-focal narrow band imaging magnifying endoscopy Abiopsy |
| 基金项目:河北省省级科技计划资助( 18277759D) |
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| 中文摘要: |
| 目的探究窄带双变焦放大内镜在胃部癌前病变及早期胃癌的诊断价值。方法回顾性分析 2019年 1月至 2020年 1月于沧州市人民医院接受胃镜检查出现病灶的 300例病人，所有病人入院即行窄带双变焦放大内镜( DF-NBI)检查和靶向活组织检查， 2周内择期再行窄带成像放大内镜( ME-NBI)检查和靶向活组织检查。比较两种内镜方法与病理学诊断结果的一致性，分析 DF-NBI下胃部癌前病变和早期癌变与 MV/MS分型的关系。结果 DF-NBI和 ME-NBI对于胃部癌前病变和早期胃癌的诊断与病理检查结果的 Kappa值分别为 0.882和 0.857，均具有较好的一致性。 DF-NBI的灵敏度为 89.4%，阳性预测值为 |
| 英文摘要: |
| Objective To explore the application value of dual-focal narrow band imaging magnifying endoscopy in gastric precancerous lesions and early gastric cancer differentiation.Methods Three hundred patients with gastric lesions underwent gastroscopy inCangzhou People′s Hospital from January 2019 to January 2020 were retrospectively analyzed. All patients underwent dual-focal narrow band imaging magnifying endoscopy (DF-NBI) examination and targeted biopsy immediately upon admission, and narrow-band imaging magnifying endoscopy (ME-NBI) examination and targeted biopsy were selected within 2 weeks. The consistency between the twoendoscopic methods and pathological diagnosis results was compared, and the relationship between gastric precancerous lesions andearly gastric cancer under DF-NBI and MV/MS classification was analyzed.Results The Kappa values of DF-NBI and ME-NBI for the diagnosis and pathological examination of gastric precancerous lesions and early gastric cancer were 0.882 and 0.857, respectively, andboth had good consistency. The sensitivity of DF-NBI was 89.4%, the positive predictive value was 87.1%, the negative predictive value was 94.1%, and the accuracy was 91.8%, which were slightly higher than ME-NBI (89.0%), and the specificity (90.7%), which were slightly lower than ME-NBI (93.1%), but the differences were not statistically significant (χ2=0.26, 0.70, P>0.05). There was significantdifference between microvessel morphology and glandular opening morphology in the diagnosis of early gastric cancer under df-nbi (χ2= 209.76, 178.81, P < 0.05).Conclusions DF-NBI and ME-NBI have high diagnostic efficiency for gastric precancerous lesions and early gastric cancer differentiation. Combining MV/MS classification can increase the detection rate of early gastric cancer, which is worthy of clinical application. |
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