| 韩雪,李莉,刘佳倪,等.正交试验优化神香草中的迷迭香酸和蒙花苷提取工艺[J].安徽医药,2023,27(2):251-254. |
| 正交试验优化神香草中的迷迭香酸和蒙花苷提取工艺 |
| Orthogonal test to optimize the extraction process of rosmarinic acid and buddleoside in Hyssopus officinalis |
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| DOI：10.3969/j.issn.1009-6469.2023.02.009 |
| 中文关键词: 神香草属植物 工艺学，制药 单因素 正交试验 迷迭香酸 蒙花苷 |
| 英文关键词: Hyssopus plant Technology,pharmaceutical Single factor Orthogonal test Rosmarinic acid Buddleoside |
| 基金项目:国家重点研究专项计划( 2018YFC1708303) |
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| 中文摘要: |
| 目的优化神香草中的迷迭香酸和蒙花苷提取条件，确定最佳的提取工艺。方法在单因素试验的基础上，采用超声法提取神香草中的迷迭香酸和蒙花苷，选取提取溶剂、提取时间、采用 L9) |
| 英文摘要: |
| Objective To optimize the extraction process of rosmarinic acid and buddleoside from Hyssopus officinalis, and to deter-mine the best extraction method.Methods Based on a single-factor test, an ultrasonic method was used to extract rosmarinic acid and buddleoside from Hyssopus officinalis. The extraction solvent, material-to-liquid ratio, extraction time, and extraction times were select-ed as the main investigating factors, and the L9(34) orthogonal test was used to optimize the extraction process of rosmarinic acid and buddleoside.Results The optimum extraction conditions were determined and operated three times in parallel. The optimal extractionprocess for rosmarinic acid and buddleoside in Hyssopus officinalis was 60% methanol as the extraction solvent, 1:20 material-to-liquid ratio, 20 min extraction time, and one extraction time.Conclusion This method is convenient, rapid, and suitable for the extraction of rosmarinic acid and buddleoside from Hyssopus officinalis. |
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