| 吴盈盈,曹立,钟平.癫痫相关认知功能障碍的机制与评估[J].安徽医药,2023,27(4):637-640. |
| 癫痫相关认知功能障碍的机制与评估 |
| The mechanism and evaluation of epilepsy related cognitive dysfunction |
| |
| DOI：10.3969/j.issn.1009-6469.2023.04.001 |
| 中文关键词: 癫痫 认知功能障碍 事件相关电位 功能磁共振成像 |
| 英文关键词: Epilepsy Cognitive dysfunction Event-related potential fMRI |
| 基金项目:国家自然科学基金项目( 81870889) |
|
| 摘要点击次数: 1765 |
| 全文下载次数: 711 |
| 中文摘要: |
| 癫痫是神经科常见且较严重的一种慢性疾病，其中 70%~80%的癫痫病人存在认知功能障碍。认知功能障碍是指注意力、记忆力以及计算能力等的下降。目前，癫痫病人认知障碍的影响因素基本明确，但其认知功能障碍的发病机制尚未完全阐明。认知功能障碍早期诊断有助于病人的后续治疗，改善生活质量。蒙特利尔认知评估量表(MoCA)、简易精神状态评价量表(MMSE)、事件相关电位( P300)以及功能磁共振成像(fMRI)等均为癫痫病人认知障碍水平的常用评估方法。该研究对癫痫认知障碍的机制及常用的评估方法进行综述。 |
| 英文摘要: |
| Epilepsy is a common and serious disease in neurology, among which 70%-80% of patients with chronic epilepsy havecognitive impairment. Cognitive impairment is a decline in attention, memory and numeracy. At present, the influencing factors of cognitive impairment in patients with epilepsy are basically clear but the pathogenesis of cognitive dysfunction has not been fully clarified.Early recognition of the extent of cognitive impairment is helpful for subsequent treatment and thus improve the quality of life of patients. Montreal Cognitive Assessment (MoCA), Simple Intelligent Mental State Scale (MMSE), Event Related Potential (P300) and functional Magnetic Resonance Imaging (fMRI) are commonly used to assess the level of cognitive impairment in patients with epilepsy. Thestudy reviews the mechanism and evaluation of epilepsy related cognitive dysfunction. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
