| 闫国珍,胡玲.亚急性甲状腺炎复发及永久性甲状腺功能减退预测因素的研究进展[J].安徽医药,2023,27(4):653-657. |
| 亚急性甲状腺炎复发及永久性甲状腺功能减退预测因素的研究进展 |
| Research progress on the predictors of recurrence and permanent hypothyroidism in subacute thyroiditis |
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| DOI：10.3969/j.issn.1009-6469.2023.04.005 |
| 中文关键词: 甲状腺炎，亚急性 甲状腺功能减退症 预测因素 治疗结果 复发 |
| 英文关键词: Thyroiditis, subacute Hypothyroidism Predictors Treatment outcome Recurrence |
| 基金项目: |
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| 中文摘要: |
| 亚急性甲状腺炎( subacute thyroiditis，SAT)是一种甲状腺炎性疾病，与病毒感染有关。其不良临床转归，即永久性甲状腺功能减退及复发的发病率似有增高趋势。复发引起的反复发热、颈部疼痛等炎性症状使病人生活质量下降，而且永久性甲状腺功能减退的病人即使终身替代治疗，也难以避免对健康的影响。预防 SAT的复发，减少永久性甲状腺功能减退，一直是学者们关注的热点。近几年，探讨 SAT不良临床转归的研究涉及甲状腺体积、甲状腺功能相关指标、人类白细胞抗原及治疗因素等方面，且出现了许多具有临床意义的新数据。尤其是 2019年至今全球大流行的新型冠状病毒是否与 SAT有关，愈发引起人们的重视。因此，该研究将从以上几方面对永久性甲状腺功能减退和复发的可能预测因素作一综述，旨在为临床工作及科研提供参考。 |
| 英文摘要: |
| Subacute thyroiditis (SAT) is an inflammatory thyroid disease associated with viral infection. The incidence of adverseclinical outcomes, i.e., permanent hypothyroidism and recurrence, seems to be increasing. Inflammatory symptoms, such as recurrent fever and neck pain caused by relapses reduce the quality of life of patients, and it is difficult to avoid health effects in patients with permanent hypothyroidism even with lifelong replacement therapy. Therefore, prevention of SAT recurrence and reduction of permanenthypothyroidism has been a hot topic of interest for scholars. In recent years, studies exploring the adverse clinical outcome of SAT haveinvolved thyroid volume, thyroid function-related indicators, human leukocyte antigens, and therapeutic factors, and many new datawith clinical implications have emerged. In particular, there is increasing interest in whether the novel coronavirus, which has been aglobal pandemic thus far in 2019, is associated with SAT. Therefore, this study will review the possible predictors of permanent hypothyroidism and recurrence from the above aspects to provide a reference for clinical work and scientific research. |
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