| 张佳佳,李国胜.发生于直肠及前列腺间并精囊侵犯后 2次手术的胃肠间质瘤 1例[J].安徽医药,2023,27(4):716-719. |
| 发生于直肠及前列腺间并精囊侵犯后 2次手术的胃肠间质瘤 1例 |
| Gastrointestinal stromal tumor occurred between rectum and prostate with seminal vesicle invasion after two operations: a case report |
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| DOI：10.3969/j.issn.1009-6469.2023.04.018 |
| 中文关键词: 胃肠道间质肿瘤(GIST) 直肠 前列腺 甲磺酸伊马替尼 |
| 英文关键词: Gastrointestinal stromal tumors (GIST) Rectum Prostate Imatinib mesylate |
| 基金项目:贵州省科技厅基金资助项目(黔科合 LH字〔 2016〕7231号) |
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| 中文摘要: |
| 目的报告发生于直肠及前列腺间的胃肠道间质瘤( gastrointestinal stromal tumor，GIST)1例。方法对贵州医科大学附属医院 2021年 11月收治的 1例 54岁男性 GIST病例进行报道并对文献复习。结果在外院被诊断为前列腺原发 GIST，随后该院影像学显示该肿块与直肠前壁关系密切，并侵犯精囊，且肠镜及直肠指检提示肿块向肠腔突出，提示直肠原发肿瘤可能性大，但病人有排尿困难症状，且术中发现肿瘤与前列腺剥离困难，不排除前列腺原发可能性。结论发生于直肠及前列腺间的 GIST，主要通过结合临床表现、影像学、病理结果及免疫组化等判断原发部位，最后可进行术中探查后综合考虑；针对此类肿瘤的治疗方案仍然以手术为主，靶向治疗提高病人无复发生存率。 |
| 英文摘要: |
| Objective To report a case of gastrointestinal stromal tumor (GIST) which occured between rectum and prostate.Meth? ods A case of GIST in a 45-year-old man admitted to the Affiliated Hospital of Guizhou Medical University in November 2021 was reported and the literature was reviewed.Results The primary prostate GIST was diagnosed and subsequently imaged. The tumor wasclosely related to the anterior wall of rectum and invaded the seminal vesicle, and colonoscopy and digital rectal examination revealed aprotrusion into the intestinal cavity, suggesting that the primary tumor was likely of rectal origin. However, the patient presented withsymptoms of dysuria and during resection the tumor was difficult to peel off from the prostate during operation, Therefore, the possibility of a primary prostate malignancy could not be ruled out.Conclusions The primary site of GIST between rectum and prostate can bejudged by combining clinical manifestation observations, imaging, pathological results and immunohistochemistry, and finally comprehensive insight can be gained from intraoperative exploration. The treatment plan for this type of tumor is still surgery-based, and targeted therapy can improve the recurrence-free survival rate of patients. |
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