| 张雨微,郭书萍,张乐.蕈样肉芽肿早期诊断的进展[J].安徽医药,2023,27(5):859-863. |
| 蕈样肉芽肿早期诊断的进展 |
| Recent advances in mycosis fungoides early diagnosis |
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| DOI：10.3969/j.issn.1009-6469.2023.05.003 |
| 中文关键词: 淋巴瘤， T细胞，皮肤 蕈样肉芽肿 诊断 组织病理 免疫组化 |
| 英文关键词: Lymphoma,T-cell,cutaneous Mycosis fungoides Diagnosis Histopathology Immunohistochemistry |
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| 中文摘要: |
| 蕈样肉芽肿( MF)是最常见的原发皮肤 T细胞淋巴瘤，临床表现多样，且早期皮损组织病理缺乏特异性，因此早期诊断较为困难，往往导致漏诊或误诊，严重影响病人的预后。现对近年来国内外关于 MF皮肤组织病理、免疫组化、 T细胞基因重排检测方法、早期诊断算法、微 RNA(MicroRNA)以及皮肤影像学等研究进展进行总结，以便及早诊断，及时治疗，改善预后。 |
| 英文摘要: |
| Mycosis fungoides (MF) is the most common type primary cutaneous T-cell lymphoma.Diagnosis of MF can be difficultdue to highly variable presentations and the sometimes nonspecific nature of histological findings in early stage.It often lead to misseddiagnosis and to misdiagnosis, which have serious consequences.This review summarizes the recent research progress of MF's histopa-thology,immunohistochemistry,T cell gene rearrangement detection method, early diagnosis algorithm, MicroRNA and skin imaging athome and abroad, which have benefits for patients in terms of earlier-stage diagnosis,offerd timely treatment and improved quality of life. |
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