| 蒋媛媛,刘岩岩,音正浪,等.术前颈部临床淋巴结阴性甲状腺微小乳头状癌中央区淋巴结转移因素分析[J].安徽医药,2023,27(6):1228-1230. |
| 术前颈部临床淋巴结阴性甲状腺微小乳头状癌中央区淋巴结转移因素分析 |
| Analysis of factors of lymph node metastasis in the central region of lymph node-negative thyroid micro papillary carcinoma |
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| DOI：10.3969/j.issn.1009-6469.2023.06.039 |
| 中文关键词: 甲状腺肿瘤 癌症早期检测 淋巴结清扫 临床颈部淋巴结阴性 中央区淋巴结 危险因素 |
| 英文关键词: Thyroid neoplasms Early detection of cancer Lymph node dissection Negative clinical neck lymph nodes Central region lymph node Risk factors |
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| 中文摘要: |
| 目的分析临床颈部淋巴结阴性( cN0)甲状腺微小乳头状癌( PTMC)病人中央区淋巴结转移的影响因素。方法选取 2019年 1月至 2021年 12月合肥市第一人民医院甲状腺乳腺外科首诊收治并由同一治疗组手术治疗行预防性中央区淋巴结清扫的 cN0期 PTMC病人 106例，回顾性分析年龄、性别、肿瘤长径、肿瘤是否多灶及桥本甲状腺炎与中央区淋巴结转移率的关系，并探讨其独立危险因素。结果 cN0期 PTMC病人中央区淋巴结转移率为 36.79%(39/106)单因素分析后发现中央区淋巴结转移与年龄、肿瘤长径、性别及多灶性相关( P<0.05)而与病人是否为桥本甲状腺炎无关，差异，无统计学意义( P>0.05)。多因素 logistic回归分析则发现性别、年龄、肿瘤长径及多灶，性仍为 cN0期 PTMC病人中央区淋巴结转移的独立危险因素。结论 |
| 英文摘要: |
| Objective To analyze the factors influencing lymph node metastasis in the central region of patients with clinical cervical lymph node-negative (cN0) thyroid micropapillary carcinoma (PTMC). Methods A total of 106 patients with cN0 stage PTMC whowere first admitted to the Department of Thyroid and Breast Surgery of Hefei First People′s Hospital from January 2019 to December2021 and were surgically treated in the same treatment group for preventive central lymph node dissection were selected, and the relationship between age, sex, tumor length and diameter, whether the tumor was multifocal and Hashimoto′s thyroiditis and central zonelymph node metastasis rate were retrospectively analyzed, and their independent risk factors were discussed. Results The central lymph node metastasis rate in patients with cN0 papillary thyroid carcinoma was 36.79% (39/106), and univariate analysis showed thatcentral lymph node metastasis was associated with age, tumor length, sex and multifocality (P<0.05) but not with Hashimoto′s thyroiditis (P>0.05). Multivariate logistic regression analysis found that sex, age, tumor length, and multifocality were still independent riskfactors for lymph node metastasis in the central region of patients with cN0 stage PTMC. Conclusion Males, patients aged < 55 years,patients with a maximum tumor diameter > 5 mm and PTMC patients with multifocal tumors were more prone to developing central region lymph node metastasis. |
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