| Objective To explore the effect of mindfulness-based decompression therapy (MBSR) on alleviating the psychologicalpain of malignant tumor patients undergoing concurrent chemoradiotherapy.Methods A total of 120 malignant tumor patients admitted to The First Affiliated Hospital of Xi′an Jiaotong University from January 2020 to June 2021 were selected and divided into anobservation group and a control group, with 60 patients in each group. The control group received routine nursing, and the observationgroup received MBSR for 8 weeks on the basis of routine nursing. The psychological distress score, psychological state and quality oflife were observed and compared between the two groups.Results Psychological pain scores: observation group: (5.49±1.88)points,(4.11±1.62)points; control group: (5.36±1.78)points, (4.71±1.24)points, the observation group decreased more obviously after intervention (P < 0.05). The pain degree in both groups was moderate, and the pain degree in both groups eases slightly after intervention, butthere was significant difference between the observation group and the observation group (P < 0.05). Scores of anxiety and depression:Compared with before intervention, both groups were significantly lower after intervention, with statistical significance (P < 0.05), thedecrease was more obvious in the observation group after intervention, there was significant difference between the two groups (P < 0.05); Quality of life score: Scores of physical health [VT: (79.51±16.42)points, (71.84±20.82)points; RE:(84.72±19.87)points, (77.29±18.51)points; SF:(85.19±20.15)points, (77.24±19.39)points; MH:(87.44±17.94)points, (80.88±17.57)points], the dimensions of physicalfunction (PF), physical function (RP) and overall self-assessment of health (GH) were slightly improved in the two groups, while thedimensions of body pain (BP) were decreased, but the differences were not statistically significant. In terms of mental health, the scoresof vitality (VT), social function (SF), emotional function (RE) and mental health (MH) in the observation group were lower than those inthe control group, and the differences were statistically significant (P < 0.05). At the end of 8 weeks after MBSR intervention, the expression levels of CD3+, CD4+, CD8+, NK cells and interleukin-6 in observation group were significantly increased, while the expression level of cortisol was significantly decreased (P < 0.05). The comparison of indexes between the two groups was also significant (P < 0.05).Conclusion Mindfulness decompression can significantly relieve the psychological pain, improve the anxiety and depression,and improve the quality of life of malignant tumor patients with concurrent chemoradiotherapy. |
