| 石海燕,李昌平,谭礼让,等.腹式深呼吸训练配合莫沙必利及奥美拉唑治疗对胃食管反流病并慢性阻塞性肺疾病肺功能和吞咽功能的影响[J].安徽医药,2023,27(8):1641-1645. |
| 腹式深呼吸训练配合莫沙必利及奥美拉唑治疗对胃食管反流病并慢性阻塞性肺疾病肺功能和吞咽功能的影响 |
| Effects of abdominal deep breathing training combined with mosapride and omeprazole on the lung function and swallowing function of patients with gastroesophageal reflux disease complicated with COPD |
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| DOI：10.3969/j.issn.1009-6469.2023.08.033 |
| 中文关键词: 胃食管反流 肺疾病，慢性阻塞性 腹式深呼吸训练 莫沙必利 奥美拉唑 肺功能 吞咽功能 |
| 英文关键词: Gastroesophageal reflux Pulmonary disease,chronic obstructive Abdominal deep breathing training Mosapride Omeprazole Lung function Swallowing function |
| 基金项目:四川省医学科研青年创新课题( Q17001) |
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| 中文摘要: |
| 目的探讨腹式深呼吸训练( ADBT)配合莫沙必利及奥美拉唑治疗对胃食管反流病( GERD)合并慢性阻塞性肺疾病(COPD)病人肺功能和吞咽功能的影响。方法选取 2019年 7月至 2020年 6月巴中市中心医院收治的 GERD合并 COPD病人 88例，按随机数字表法分为对照组(n=44，予莫沙必利与奥美拉唑)与观察组( n=44，在对照组基础上联合 ADBT)。比较两组反流性疾病问卷( RDQ)评分、圣乔治呼吸问卷( SGRQ)评分、肺功能［肺活量( FVC)、第 1秒用力呼气容量( FEV1)、最大吸气压(MIP)、最大呼气压( MEP)］、吞咽功能、括约肌功能、随访 1年 COPD急性加重发作率。结果治疗后两组 RDQ评分、 SGRQ评分、上段食管括约肌( UES)静息压均低于治疗前( P<0.05)且治疗后观察组 RDQ评分［( 13.39±4.01)分比( 19.28±4.93)分］、 SGRQ评分［(118.08±18.22)分比( 137.59±15.77)分］、 UES静息，压［(40.72±4.49)mmHg比( 52.96±5.49)mmHg］均低于对照组( P< |
| 英文摘要: |
| Objective To investigate the effects of abdominal deep breathing training (ADBT) combined with mosapride andomeprazole on the lung function and swallowing function of patients with gastroesophageal reflux disease (GERD) complicated withchronic obstructive pulmonary disease (COPD).Methods Eighty-eight patients with GERD complicated with COPD admitted to Bazhong Central Hospital from July 2019 to June 2020 were selected and assigned into control group (n=44, given mosapride and omepra zole) and study group (n=44, combined with ADBT on the basis of the control group) according to the random number table method. Thetwo groups were compared in the reflux disease questionnaire (RDQ) scores, St. George's Respiratory Questionnaire (SGRQ) scores,lung function [vital capacity (FVC), forced expiratory volume in the first second (FEV1), maximum inspiratory pressure (MIP), maximum Expiratory pressure (MEP)], swallowing function, sphincter function, and the incidence of acute exacerbations of COPD during the1-year follow-up.Results After treatment, the RDQ score, SGRQ score, and upper esophageal sphincter (UES) resting pressure of thetwo groups were lower than before treatment (P<0.05), and the RDQ score [(13.39±4.01) vs. (19.28±4.93)], SGRQ score [(118.08± 18.22) vs. (137.59±15.77)], and UES resting pressure [(40.72±4.49) mmHg vs. (52.96±5.49) mmHg] of the study group after treatment were all lower than those of the control group (P<0.05). After treatment, the FVC, FEV1, MIP, MEP, and lower esophageal sphincter(LES) resting pressure in the two groups were all higher than before treatment (P<0.05), and the FVC, FEV1, MIP, MEP, LES resting pressure in the study group were all higher than that in the control group (P<0.05). After treatment, the swallowing function of the two groups was better than before treatment (P<0.05), and the swallowing function of the study group was better than that of the control group after treatment (P<0.05). After treatment, the length of LES in the two groups was longer than before treatment (P<0.05), and the length of LES in the study group was longer than that in the control group after treatment (P<0.05). During the follow-up period, theacute exacerbation rate of COPD in the study group 18.18% (8/44) was lower than 40.91% (18/44) in the control group (P<0.05).Con clusion ADBT combined with mosapride and omeprazole in the treatment of GERD with COPD can relieve the symptoms of GERD,improve lung function, swallowing function, and sphincter function, reduce the number of acute exacerbations of COPD during follow-up, and improve the quality of life of patients. |
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