| 魏千城,李海峰.调神法针刺联合现代康复疗法对男性慢性盆腔疼痛综合征的效果观察[J].安徽医药,2023,27(9):1779-1783. |
| 调神法针刺联合现代康复疗法对男性慢性盆腔疼痛综合征的效果观察 |
| Effect of Tiaoshen acupuncture combined with modern rehabilitation therapy on male chronic pelvic pain syndrome |
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| DOI：10.3969/j.issn.1009-6469.2023.09.018 |
| 中文关键词: 慢性盆腔疼痛综合征 调神法针刺 现代康复疗法 男性 负性情绪 炎症 |
| 英文关键词: Chronic pelvic pain syndrome Tiaoshen acupuncture Modern rehabilitation therapy Male Negative emotions Inflammation |
| 基金项目:湖北省卫生健康委科研项目( ZY2021Q015) |
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| 中文摘要: |
| 目的探讨调神法针刺联合现代康复疗法对男性慢性盆腔疼痛综合征的效果。方法选取 2020年 10月至 2021年 10月十堰市太和医院收治的 86例男性慢性盆腔疼痛综合征病人，按随机数字表法分为两组。对照组 43例采用现代康复疗法治疗，联合组 43例给予调神法针刺联合现代康复疗法治疗，两组均治疗 4周。采用视觉模拟评分法( VAS)评估比较两组病人治疗前、治疗 1周后、 2周后、 4周后的疼痛情况，对比两组治疗期间急性疼痛发作次数；采用汉密尔顿抑郁量表( HAMD)、汉密尔顿焦虑量表(HAMA)评估比较两组病人治疗前后抑郁和焦虑情绪；对比两组病人治疗前后血清中白细胞介素 -6(IL-6)、前列腺素 E2(PGE2)、核因子 κB(NF-κB)水平的变化及治疗期间不良反应发生情况。结果 VAS值在组间、时间、交互方面比较均差异有统计学意义( P<0.05)，联合组治疗 1周后、 2周后、 4周后 VAS值分别为( 3.54±0.65)分、(2.51±0.53)分、(1.86±0.37)分低于对照组相应的 VAS值(4.01±0.72)分、(3.04±0.58)分、(2.33±0.44)分；两组治疗后 VAS值均低于治疗前(P<0.05)治疗 2周后、 4周后 VAS值均低于 1周后( P<0.05)治疗 4周后 VAS值均低于 2周后( P<0.05)；治疗后不同时刻联合组 VAS值均低，于对照组( P<0.05)。联合组治疗期间急性疼作次数低于对照组( P<0.05)；治疗后两组 HAMD、HAMA评分均较治疗前降低( P<0.05)，且联合组均低于对照组( P<0.05)。治疗后两组血清 IL-6、PGE2、NF-κB水平均降低(P<0.05)，且联合组治疗后血清指标水平均低于对照组(P<0.05)；两组不良反应发生率差异无统计学意义( P>0.05)。结论对男性慢性盆腔疼痛综合征病人采取调神法针痛发，刺联合现代康复疗法治疗可明显缓解疼痛和改善焦虑、抑郁情绪，降低血清 IL-6、PGE2、NF-κB水平，且保障了一定安全性。 |
| 英文摘要: |
| Objective To explore the effect of Tiaoshen acupuncture combined with modern rehabilitation therapy on male chronic pelvic pain syndrome.Methods Totally 86 patients with male chronic pelvic pain syndrome treated in Taihe Hospital, Shiyan Cityfrom October 2020 to October 2021 were selected and assigned into two groups according to the random number table method. The con-trol group (n=43) were treated with modern rehabilitation therapy, while the combined group (n=43) were treated with Tiaoshen acu- puncture combined with modern rehabilitation therapy. Both groups were treated for 4 weeks. Visual analogue scale (VAS) was used toevaluate and compare the pain of the two groups before treatment, 1 week, 2 weeks, 4 weeks after treatment, and the number of acutepain attacks during treatment were compared between the two groups. Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale(HAMA) were used to evaluate and compare the depression and anxiety of the two groups before and after treatment. The changes of se-rum levels of interleukin-6 (IL-6), prostaglandin E2 (PGE2), nuclear factor-κB (NF-κB) before and after treatment and the occurrence of adverse reactions during treatment were compared between the two groups.Results There were significant differences in VAS value among groups, time and interaction (P < 0.05). The VAS values of the combined group 1 week, 2 weeks and 4 weeks after treatmentwere (3.54±0.65), (2.51±0.53), and (1.86±0.37) respectively, which were lower than the corresponding VAS values of the control group[(4.01±0.72), (3.04±0.58) and (2.33±0.44), respectively]. The VAS values of the two groups after treatment were lower than those beforetreatment; the VAS values 2 weeks and 4 weeks after treatment were lower than those 1 week after treatment (P < 0.05), and the VAS values 4 weeks after treatment were lower than those 2 weeks after treatment (P < 0.05). The VAS values of the combined group were lower than those of the control group at different times after treatment (P < 0.05). The number of acute pain attacks during treatment in the combined group was lower than that in the control group (P < 0.05). After treatment, HAMD and HAMA scores in the two groups were lower than those before treatment (P < 0.05), and the scores in the combined group were lower than those in the control group (P < 0.05). After treatment, the levels of serum IL-6, PGE2 and NF-κB in the two groups all decreased (P < 0.05), and the above indexes in the combined group were lower than those in the control group (P < 0.05). There was no significant difference in the incidence rate of adverse reactions in the two groups (P > 0.05).Conclusion The application of Tiaoshen acupuncture combined with modern rehabilita-tion therapy in the treatment of male patients with chronic pelvic pain syndrome can significantly alleviate pain, improve anxiety anddepression, reduce the levels of serum IL-6, PGE2 and NF-κB, and ensure a certain degree of security. |
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