| 章爱华,高文霞,姚世文.心脏 CT血管成像中碘对比剂浓度对肥胖病人冠状动脉检查图像质量、肾功能及碘用量的影响[J].安徽医药,2023,27(9):1800-1803. |
| 心脏 CT血管成像中碘对比剂浓度对肥胖病人冠状动脉检查图像质量、肾功能及碘用量的影响 |
| Effect of iodine contrast concentration on image quality, renal function and iodine dosage of coronary artery examination in obese patients in cardiac CT angiography |
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| DOI：10.3969/j.issn.1009-6469.2023.09.023 |
| 中文关键词: 冠状血管造影术 冠心病 肥胖 CT血管成像 碘对比剂 浓度 图像质量 |
| 英文关键词: Coronary angiography Coronary artery disease Obesity CT angiography Iodine contrast agent Concentra- tion Image quality |
| 基金项目:江苏省优势学科建设工程项目( YSHL0803-443) |
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| 中文摘要: |
| 目的探讨心脏 CT血管成像( CTA)中不同碘对比剂浓度对肥胖病人冠状动脉检查图像质量、不良反应发生率及碘用量的影响。方法选取 2021年 1月至 2022年 3月如皋市人民医院 100例行心脏 CTA检查的肥胖冠心病病人，以抽签法随机分为两组，各 50例。对照组 CTA检查中碘对比剂浓度为 370 mgI/mL，研究组 CTA检查中碘对比剂浓度为 350 mgI/mL。比较两组图像质量、图像 CT值、对比剂参数、肾功能指标。结果研究组图像质量评分及各血管段评分与对照组比较，差异无统计学意义( P>0.05)；研究组噪声( 30.25±4.12)低于对照组( 40.78±8.37)，差异有统计学意义( P<0.05)，两组信噪比及对比噪声比(CNR)、图像 CT值比较，差异无统计学意义( P>0.05)；研究组碘摄入量( 17.44±2.14)g，低于对照组的( 126.33±2.37)g，差异有统计学意义(P<0.05)研究组对比剂总量、注射流率、碘流率低于对照组，差异有统计学意义( P<0.05)；两组检查后肾功能指标比较，差异无统计学意义，(P>0.05)。结论与高浓度碘对比剂比较，肥胖病人行心脏 CTA检查中采用低浓度碘对比剂在保障图 |
| 英文摘要: |
| Objective To investigate the effects of different iodine contrast concentrations in cardiac computed tomography angiog-raphy (CTA) on the image quality, incidence of adverse reactions and iodine dosage of coronary artery examination in obese patients.Methods A total of 100 obese patients with coronary artery disease who underwent cardiac CTA examination in Rugao People's Hos-pital from January 2021 to March 2022 were selected and randomly divided into two groups of 50 cases each by the lottery method. Theconcentration of iodine contrast in CTA examination in the control group was 370 mgI/mL, and that in the study group was 350 mgI/mL.Image quality, image CT values, contrast parameters, and renal function indexes were compared between the two groups. Results There was no statistically significant difference between the image quality score and each vascular segment score of the study group andthe control group (P>0.05); the noise in the study group (30.25±4.12) was lower than that in the control group (40.78±8.37), with a sta-tistically significant difference (P<0.05), and there was no statistically significant difference between signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR), and the image CT value of the two groups (P>0.05); iodine intake in the study group (17.44±2.14) g waslower than that in the control group (126.33±2.37) g, and the difference was statistically significant (P<0.05); the total amount of con-trast, injection flow rate and iodine flow rate in the study group were lower than those in the control group, and the difference was statis-tically significant (P<0.05); and there was no significant difference in renal function indexes between the two groups after examination (P>0.05).Conclusion Compared with high-concentration iodine contrast medium, the use of low-concentration iodine contrast medi- um in cardiac CTA examination in obese patients can reduce noise under the premise of guaranteeing image quality, and can reducethe total amount of contrast medium and iodine intake, which is feasible and clinically relevant. |
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