| 李静静.心率变异性和QT间期离散度在血管迷走性晕厥中的诊断价值[J].安徽医药,待发表. |
| 心率变异性和QT间期离散度在血管迷走性晕厥中的诊断价值 |
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| 投稿时间：2023-10-06 录用日期：2023-12-02 |
| DOI： |
| 中文关键词: 血管迷走性晕厥 心率变异性 QT间期离散度 |
| 英文关键词: |
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| 中文摘要: |
| 目的 探讨心率变异性（heart rate variability,HRV）和QT间期离散度（QT interval dispersion,QTd）对血管迷走性晕厥患儿（vasovagal syncope,VVS）诊断效能。 方法 选取2019年9月～2023年5月因晕厥到徐州市中心医院儿童晕厥专病门诊就诊或住院，通过直立倾斜试验（head-up tilt table test,HUTT）明确诊断为的VVS的儿童69例为VVS组，同时期在徐州市中心医院体检的健康儿童69例为对照组。VVS组和对照组均进行24h动态心电图和12导联心电图检查。采用SPSS 26.0统计软件进行数据处理。结果 VVS组标准差均值（SDNNi）、差值均方根（rMSSD）、低频功率（LF）、高频功率（HF）、极低频功率（VLF）高于对照组，差异有统计学意义（P＜0.05）。与对照组相比，VVS组最大QT间期（QTmax）、最小QT间期（QTmin）、QT间期离散度（QTd）、校正最大QT间期（QTcmax）、校正最小QT间期（QTcmin）、校正QT间期离散度（QTcd）延长, 差异有统计学意义（P<0.05）。绘制受试者操作者特征（receiver operating characteristic, ROC）曲线，结果显示VLF、QTd以及二者联合诊断的曲线下面积（AUC)分别为0.801、0.864、0.914，两种指标联合诊断的AUC高于单个指标。结论 HRV部分指标和QTd对预测HUTT诊断儿童血管迷走性晕厥具有一定的价值,VLF联合QTd能提高对VVS的诊断效能。 |
| 英文摘要: |
| Objecive To investigate the diagnostic efficacy of heart rate variability (HRV) and QT interval dispersion (QTd) in children with vasovagal syncope (VVS).Methods A total of 69 children who visited or were hospitalized in the syncope outpatient clinic of Xuzhou Central Hospital between September 2019 and May 2023 and were diagnosed as VVS by head-up tilt table test (HUTT) due to syncope were selected as a vasovagal syncope group. A control group consisted of 69 healthy children who visited Xuzhou Central Hospital for medical check-ups during the same period. A 12-lead electrocardiogram and a 24-hour ambulatory electrocardiogram were performed on the vasovagal syncope and control groups. The statistical program SPSS 26.0 was utilized to process the data.Results The mean of the SD of all NN intervals for all 5-minute segments (SDNNi), square root of the mean of the sum of squares of differences between adjacent NN intervals (rMSSD), low-frequency power (LF), high-frequency power (HF), and very low-frequency power (VLF) of the VVS group were higher than those of the control group, and the differences were statistically significant (P<0.05). In the VVS group, there were statistically significant (P<0.05) differences in the maximum QT interval (QTmax), minimum QT interval (QTmin), QT interval dispersion (QTd), corrected maximum QT interval (QTcmax), corrected minimum QT interval (QTcmin), and corrected QT interval dispersion (QTcd) when compared to the control group. Draw receiver operating characteristic (ROC) curves for the subjects, and the results show that the area under the curve (AUC) for VLF, QTd, and their combined diagnosis are 0.801, 0.864, and 0.914, respectively, and the AUC of the combined diagnosis of the two indexes was higher than that of the single index.Conclusions HRV partial indices and QTd are valuable in predicting HUTT for the diagnosis of vasovagal syncope in children, VLF combined with QTd improves diagnostic efficacy in VVS. |
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