| 宗桂娟,赵敏,陈旭东.原发子宫内膜卵黄囊瘤 1例并文献回顾[J].安徽医药,2023,27(10):2038-2040. |
| 原发子宫内膜卵黄囊瘤 1例并文献回顾 |
| Primary yolk sac tumor of the endometrium: a case report and literature review |
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| DOI：10.3969/j.issn.1009-6469.2023.10.028 |
| 中文关键词: 内胚层窦瘤 子宫内膜卵黄囊瘤 甲胎蛋白(AFP) 病理学 临床治疗 |
| 英文关键词: Endodermal sinus tumor Endometrial yolk sac tumor Alpha-fetal protein(AFP) Pathology Clinical therapy |
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| 中文摘要: |
| 目的提高对原发子宫内膜卵黄囊瘤( yolk sac tumor，YST)临床及病理学特征的认识。方法报告南通市肿瘤医院 2020年 5月诊断 YST 1例，收集病人相关临床信息包括血清甲胎蛋白( AFP)水平、手术方案、化学治疗方案及术后随访 20个月。并复习原发子宫内膜 YST相关文献。结果原发性子宫内膜 YST 1例，采取全子宫加双侧附件切除手术、网膜切除术及盆腔淋巴结清扫术，并在术后化疗接受 BEP(博来霉素，依托泊苷和顺铂)治疗方案，随访 20个月，病人预后佳。结论原发性子宫内膜 YST是一种罕见高度恶性的生殖细胞肿瘤，迄今为止尚未有共识性治疗方案。手术治疗联合术后化疗被认为是治疗原发性子宫内膜 YST的有效方法。术后随访血清 AFP水平可用于监测治疗结果以及检测治疗后的转移和复发。 |
| 英文摘要: |
| Objective To improve the understanding of clinical and pathological features of primary endometrial Yolk Sac Tumor (YST).Methods One patient with YST who was diagnosed in Nantong Tumor Hospital in May 2020 was reported, the relevant clinicalinformation of the patient, including serum AFP levels, surgical plan, chemotherapy plan, and postoperative follow-up for 20 months were collected. And the relevant literature on primary endometrial YST was reviewed.Results One case of primary endometrial YSTwas treated with total hysterectomy plus bilateral adnexectomy, epiploidectomy and pelvic lymph node dissection, and bleomycin, etoposide and cisplatin (BEP) after postoperative chemotherapy. The patient achieved a relatively good prognosis during the follow-up period of 20 months.Conclusion Primary endometrial YST is a rare highly malignant germ cell tumor, so far there is no consensus treatment plan. Surgical treatment combined with postoperative chemotherapy is considered to be an effective method for treating primaryendometrial YST. Serum AFP levels at postoperative follow-up can be used to monitor the treatment outcome and detect metastasis and relapse after treatment. |
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