| 郭悦劼,谢勇.全身免疫炎症指数、 EGRIS评分对吉兰 -巴雷综合征病人发生呼吸衰竭的预测价值[J].安徽医药,2023,27(11):2241-2244. |
| 全身免疫炎症指数、 EGRIS评分对吉兰 -巴雷综合征病人发生呼吸衰竭的预测价值 |
| Predictive value of systemic immune inflammation index and EGRIS score for respiratory failure in patients with Guillain-Barre syndrome |
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| DOI：10.3969/j.issn.1009-6469.2023.11.027 |
| 中文关键词: 吉兰 -巴雷综合征 全身免疫炎症指数 Erasmus GBS呼吸功能不全评分 呼吸衰竭 |
| 英文关键词: Guillain Barr′e syndrome Systemic immune index Erasmus GBS respiratory insufficiency score(EGRIS) Respiratory failure |
| 基金项目:湘南学院校级科研课题 (2018XJ64) |
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| 中文摘要: |
| 目的探讨全身免疫炎症指数( SII)、 Erasmus GBS呼吸功能不全评分( EGRIS)对吉兰 -巴雷综合征( GBS)病人呼吸衰竭发生的预测价值。方法收集 2018年 5月至 2021年 5月在郴州市第一人民医院接受治疗的 123例 GBS病人的临床资料。根据是否发生呼吸衰竭分为呼吸衰竭组、非呼吸衰竭组。对比两组病人的 EGRIS评分、 SII；运用多因素 logistic回归分析探究可能影响 GBS病人呼吸衰竭的危险因素；使用受试者操作特征( ROC)曲线评估 EGRIS、SII对 GBS病人发生呼吸衰竭的预测价值。结果两组病人发病到住院时间［( 5.3±0.6)d比( 9.2±1.1)d］、 EGRIS评分［( 5.5±0.2)分比( 2.8±0.3)分］及 SII［( 1 683.6±64.3)分比(603.4±25.2分)］比较，差异有统计学意义( P<0.05)。 EGRIS及 SII是 GBS病人发生呼吸衰竭的危险因素( OR值分别为 1.43、5.26，均 P<0.01)。 EGRIS、SII及两者联合预测呼吸衰竭的曲线下面积分别为 0.75、0.89、0.93，灵敏度分别为 82.01%、96.67%、95.33%，特异度分别为 69.01%、67.61%、78.87%。结论 EGRIS、SII是预测 GBS病人发生呼吸衰竭的指标，两者联合可准确预测呼吸衰竭风险。 |
| 英文摘要: |
| Objective To investigate the predictive value of systemic immune inflammation index (SII) and Erasmus GBS respiratory insufficiency score (EGRIS) in the occurrence of respiratory failure in patients with Guillain-Barr′e syndrome (GBS).Methods The clinical data of 123 patients with GBS treated in the First People′s Hospital of Chenzhou from May 2018 to May 2021 were collected.According to whether respiratory failure occurred, they were divided into respiratory failure group and non-respiratory failure group.The EGRIS score and SII between the two groups were compared. Multivariate logistic regression analysis was used to analyze the riskfactors of respiratory failure. Receiver operator characteristic curve (ROC) was used to analyze the predictive value of EGRIS and SII onrespiratory failure.Results There were significant differences in the time from onset to hospitalization [(5.3±0.6) d vs. (9.2±1.1) d], EGRIS score [(5.5±0.2) vs. (2.8±0.3)] and SII [(1 683.6±64.3) vs. (603.4±25.2)] between two groups (P<0.05). EGRIS and SII were risk factors for respiratory failure in patients with GBS (OR values 1.43 and 5.26, respectively, P<0.01). The areas under the curve ofEGRIS, SII and their combination in predicting respiratory failure were 0.75,0.89 and 0.93, respectively, the sensitivity were 82.01%,96.67% and 95.33%, respectively, and the specificity were 69.01%, 67.61% and 78.87%, respectively.Conclusions EGRIS and SII are the indicators to predict respiratory failure in patients with GBS. The combination of EGRIS and SII can accurately predict the riskof respiratory failure. |
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