| Objective To analyze the influencing factors of patients with liver cirrhosis and sarcopenia.Methods A total of 215 in? patients with liver cirrhosis in the Fourth Affiliated Hospital of Xinjiang Medical University from 2021 June to May 2022 were selected.Demographic information, serological parameters, etiology, cirrhosis-related complications, CTP score, MELD and other clinical datawere collected. At the same time, nutritional risk screening and nutritional assessment including dominant handgrip strength, gaitspeed, triceps skinfold thickness (TSF), upper arm circumference, upper arm muscle circumference (AMC) and calf circumference wereperformed. The CT images of L3 were collected and analyzed by Elida clinical imaging analysis system (RADinfo SYSTEMS), and theskeletal muscle mass index (SMI) was calculated. The diagnostic criteria of sarcopenia was L3-SMI<50 cm2/m2 (male) or<39 cm2/m2 (fe? male). The patients were assigned into sarcopenia group and non-sarcopenia group, and multivariate logistic regression analysis was used to screen the influencing factors of Sarcopenia.Results The incidence of myasthenia gravis in hospitalized patients with cirrhosiswas 68.3%. There were significant differences in age, ascites, esophageal varicose veins bleeding, low MELD risk (≤14 points), highMELD risk (> 18 points),RBC and HGB of the serological indexes,nutritional score, nutritional risk, BMI, dominant hand grip strength,arm circumference, leg circumference, TSF and AMC in nutrition risk assessment between the two groups (P < 0.05). The dominant hand grip strength of the patients with non-sarcopenia syndrome was 32.25 (19.70, 45.62), which was significantly higher than that ofthe patients with sarcopenia syndrome 13.50 (5.33, 40.83). Multivariate Logistic regression analysis showed that nutritional score≥3points [OR=1.78, 95%CI (1.28, 2.48), P=0.001] and BMI [OR=0.69, 95%CI (0.61, 0.77), P<0.001] were the influencing factors in liv? er cirrhosis patients combined with sarcopenia.Conclusion Nutritional score and low BMI are the influencing factors in hospitalized patients with liver cirrhosis combined with sarcopenia. |
