文章摘要
王一涵,孙晓祥,王继兵.青光眼滤过术中植入物的应用现状[J].安徽医药,2024,28(6):1066-1071.
青光眼滤过术中植入物的应用现状
Application status of implants in glaucoma filtering surgery
  
DOI:10.3969/j.issn.1009-6469.2024.06.002
中文关键词: 青光眼引流植入物  青光眼  滤过性手术  纤维化  抗瘢痕化治疗  植入物
英文关键词: Glaucoma drainage implants  Glaucoma  Filtering surgery  Fibrosis  Antiscarring therapy  Implants
基金项目:潍坊市卫生健康委员会科研项目计划( WFWSJK-2001-002)
作者单位E-mail
王一涵 潍坊医学院临床医学院山东潍坊 261000  
孙晓祥 潍坊医学院临床医学院山东潍坊 261000  
王继兵 潍坊医学院临床医学院山东潍坊 261000 wangjb918@163.com 
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中文摘要:
      滤过性手术是目前治疗青光眼的主要手术方式,滤过泡瘢痕化是导致手术失败的主要原因。术中及术后应用抗代谢药物如丝裂霉素 C(MMC)和 5-氟尿嘧啶能够提高手术成功率,但相关并发症难以避免。动物实验与临床应用证实植入物的应用能有效保持滤过道通畅,将植入物赋予缓释抗代谢或抗瘢痕化的能力将会增强青光眼滤过手术的效果。该研究将对各种植入物在青光眼滤过手术中的应用作一综述。
英文摘要:
      Currently, glaucoma filtering surgery (GFS) is the main surgical method for the treatment of glaucoma, in which scarring ofthe filtration vesicle is the main cause of surgical failure. Intraoperative and postoperative application of antimetabolites such as mitomycin C (MMC) and 5-fluorouracil can improve the success rate of surgery, but the related complications are difficult to avoid. Animalstudies and clinical applications have confirmed that the application of implants can effectively keep the filter channel open, and endowing implants with slow-release antimetabolism or antiscarring capabilities will enhance the outcome of glaucoma filtering surgery.This study will summarize the application of various implants in glaucoma filtering surgery.
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