| 罗雪彬,韩蜜,龙远雄.中医药治疗鼻咽癌研究文献可视化分析[J].安徽医药,2024,28(8):1675-1680. |
| 中医药治疗鼻咽癌研究文献可视化分析 |
| Visualization analysis of research literature on traditional Chinese medicine treatment of nasopharyngeal carcinoma |
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| DOI：10.3969/j.issn.1009-6469.2024.08.041 |
| 中文关键词: 鼻咽肿瘤 中医药 VOSviewer CiteSpace 可视化 |
| 英文关键词: Nasopharyngeal neoplasms Chinesemedicine VOSviewer CiteSpace Visualization |
| 基金项目:湖南省自然科学基金项目( 2022JJ70104)；湖南省教育厅科学研究优秀青年项目( 21B0372)；湖南省中医药科研计划青年项目( 2021162)；湖南省卫健委科研计划项目( D202302048885)；湖南中医药大学校级科研基金( 2022XYLH015) |
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| 中文摘要: |
| 目的对国内中医药治疗鼻咽癌研究文献进行计量研究，分析热点与主题演变。方法检索中国知网、万方、维普发表的中医药治疗鼻咽癌研究文献，利用 VOSviewer1.6.18和 CiteSpace5.0.R7软件对文献中作者、机构、关键词:进行统计，构建知识图谱，总结现状与热点及研究趋势。结果 1987年至今国内发文总量共 1 146篇，发文作者共 3 016人，聚类为 11个团队；发文机构共 724个，主要集中在湖南、广东、广西三省；研究热点主要围绕放疗、化疗、中西医结合疗法为代表治疗方式以及以细胞增殖、凋亡等鼻咽癌致病机制研究；聚焦分子机制研究、临床研究、中医治法理论、数据挖掘四个方面；主题演变主线为“中医药或中西医结合治疗 -中医药结合放化疗临床研究 -基础研究”，中西医结合疗法、网络药理学与机制研究仍将是未来的发展趋势。结论近年来研究数量有所上升，但研究团队、研究机构之间存在一定的学术壁垒，建议加强跨地区的合作交流，深入探索鼻咽癌发病的机制机理，开展多中心研究合作，提供更多的循证医学证据；深化基础研究，加大基础向临床研究的转化力度；在临床方面，致力于提高临床疗效，充分发挥中医特色优势，探索建立统一的诊疗方案以及疗效评价标准。 |
| 英文摘要: |
| Objective To conduct quantitative research on the domesticliterature on the treatment of nasopharyngeal carcinoma withtraditional Chinese medicine,and analyze the evolution of hotspots and themes.Methods Literature on traditional Chinese medicine treatment of nasopharyngeal carcinoma published by CNKI, Wanfang, and VIP were retrieved. By using VOSviewer 1.6.18 andCiteSpace 5.0.R7 software to statistically analyze authors, institutions, and Key words:in the literature, a knowledge graph was construct-ed, and the current situation, hotspots, and research trends were summarized.Results Since 1987, the total number of articles pub-lished in China has been 1 146. There were 3 016 authors, clustered into 11 teams; There were 724 document issuing agencies, mainlyin Hunan, Guangdong and Guangxi provinces; The research focused mainly on the representative treatment methods of radiotherapy,chemotherapy and integrated traditional Chinese and Western medicine, as well as the pathogenic mechanism of nasopharyngeal carci-noma such as cell proliferation and apoptosis; Focusing on molecular mechanism research, clinical research, TCM treatment theory anddata mining; The main theme evolution was "traditional Chinese medicine or integrated traditional Chinese and Western medicine treat-ment -clinical research of integrated traditional Chinese medicine radiotherapy and chemotherapy -Basic Research". Integrated tradi-tional Chinese and Western medicine therapy, network pharmacology and mechanism research will still be the development trend in thefuture.Conclusions In recent years, the number of studies has increased, but there are certain academic barriers between researchteams and research institutions. It is suggested to strengthen cross regional cooperation and exchange, deeply explore the pathogenesisof nasopharyngeal carcinoma, carry out multi center research cooperation, and provide more evidence-based medical evidence; Deepenbasic research and strengthen the transformation from basic research to clinical research; In the clinical aspect, we are committed to im-proving the clinical efficacy, giving full play to the characteristic advantages of traditional Chinese medicine, and exploring the estab-lishment of a unified diagnosis and treatment scheme and efficacy evaluation criteria. |
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