| 江轩,夏金翔,黄志文,等.氢质子磁共振波谱分析在排尿困难伴有逼尿肌收缩乏力中的诊断价值[J].安徽医药,2024,28(11):2184-2187. |
| 氢质子磁共振波谱分析在排尿困难伴有逼尿肌收缩乏力中的诊断价值 |
| Diagnostic value of hydrogen proton magnetic resonance spectroscopy techniques for the diagnosis of detrusor underactivity |
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| DOI：10.3969/j.issn.1009-6469.2024.11.014 |
| 中文关键词: 排尿困难 膀胱逼尿肌 逼尿肌收缩乏力 下尿路症状 磁共振波谱成像 膀胱 |
| 英文关键词: Dysuria Detrusor of bladder Detrusor underactivity Lower urinary tract symptoms Magnetic resonance spectroscopy Bladder |
| 基金项目:国家自然科学基金资助项目( 82000672)；安徽省重点研发与开发项目( 2022e07020062)；合肥市卫健委应用医学项目( Hwk2022zd006) |
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| 中文摘要: |
| 目的探索氢质子磁共振波谱分析技术在逼尿肌收缩乏力( DU)中的诊断价值。方法收集 2022年 7月至 2023年 7月合肥市第二人民医院非神经源性下尿路症状( LUTS)病人 42例，根据尿动力学检查结果分为 DU组 20例和非 DU组 22例。所用设备为 Siemens Prisma 3.0T磁共振成像系统。记录膀胱壁内胆碱( Cho)和肌酸( Cr)的峰值积分数据，并通过后处理软件得出 Cho与 Cr的峰值积分比值( Cho/Cr)，进行组间比较。结果 DU组 Cho/Cr最大比值 1.30，最小比值 0.45，平均比值 0.77±0.33，非 DU组 Cho/Cr最大比值 1.62，最小比值 0.53，平均比值 1.16±0.33，DU病人 Cho/Cr与非 DU病人 Cho/Cr差异有统计学意义( P< |
| 英文摘要: |
| Objective To explore the diagnostic value of hydrogen proton magnetic resonance spectroscopy techniques for the diagnosis of detrusor underactivity (DU).Methods Patients with non-neurogenic lower urinary tract symptoms (LUTS) were collected in Hefei Second People's Hospital from July 2022 to July 2023 and divided into DU and non-DU groups based on urodynamic findings, with a total of 42 patients, including 20 DU patients and 22 non-DU patients. The equipment used was Siemens Prisma 3.0T magnetic resonance imaging system. Peak integral data of choline (Cho) and creatine (Cr) within the bladder wall were recorded and the peak integralratio of Cho to Cr (Cho/Cr) was derived by post-processing software for comparison between groups.Results The DU group had a maximum Cho/Cr ratio of 1.30, a minimum ratio of 0.45, and an average ratio of 0.77±0.33. The non-DU group had a maximum Cho/Cr ratioof 1.62, a minimum ratio of 0.53, and an average ratio of 1.16±0.33. Statistical analysis showed a significant difference in Cho/Cr ratiobetween the DU group and the non-DU group (P<0.05), with the non-DU group showing a significantly higher index. However, therewas no statistically significant difference in Cho values between the DU group and the non-DU group (P>0.05).Conclusion The bladder wall urethral muscle Cho/Cr index has a correlation with bladder function and may be an objective marker for DU patients. |
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