| 薛萌,鲁娴,王然,等.入院及围术期红细胞分布宽度变化与老年髋部骨折预后的关系[J].安徽医药,2024,28(11):2245-2249. |
| 入院及围术期红细胞分布宽度变化与老年髋部骨折预后的关系 |
| Relationship between red blood cell distribution width on admission and perioperative changes and prognosis in elderly hip fracture patients |
| |
| DOI：10.3969/j.issn.1009-6469.2024.11.027 |
| 中文关键词: 髋骨折 老年病人 手术 红细胞分布宽度 预后 |
| 英文关键词: Hip fractures Elderly patients Surgery Red blood cell distribution width Prognosis |
| 基金项目: |
|
| 摘要点击次数: 476 |
| 全文下载次数: 7 |
| 中文摘要: |
| 目的探究入院及围术期红细胞分布宽度( RDW)变化与老年髋部骨折预后的关系。方法回顾性收集 2018年 1月至 2020年 3月在徐州医科大学附属医院行髋部骨折手术治疗的老年病人 650例的病历资料，收集年龄、性别、身体质量指数(BMI)、查尔森合并症指数( CCI)、骨折类型、入院 RDW以及围术期 ΔRDW(术后最高 RDW与入院 RDW差值)等信息，通过 LASSO回归与多因素 Cox回归分析病人病死率相关的危险因素。结果 650例病人根据排除标准剔除 264例，最终纳入分析共 386例。该队列中病人术后 1年病死率为 10.36%(40/386)，2年病死率为 16.06%(62/386)，4年病死率为 23.58%(91/386)，随访期病死率为 26.17%(101/386)。LASSO回归分析结果显示年龄、 CCI、入院血红蛋白、白蛋白、 RDW和 ΔRDW这 6个变量为影响老年髋部骨折手术病人病死率的特征变量；多因素 Cox回归分析结果显示年龄 75~<85岁［HR=2.17，95%CI:(1.27，3.73)，P=0.004］、年龄≥85岁［HR=3.73，95%CI:(2.11，6.62)，P<0.001］、 CCI≥2分［HR=3.58，95%CI:(2.15，5.95)，P<0.001］、入院 RDW>13.55%［HR=1.61，95%CI:(1.07，2.41)P=0.022］及 ΔRDW>0.89%［HR=3.10，95%CI:(2.00，4.79)P<0.001］是老年髋部骨折手术病人病死率的危险因素。结论≥75岁、 CCI≥2分、入院 RDW>13.55%以及 ΔRDW>0.89老年髋部骨折手术病人病年龄，%是，死率的独立危险因素。 |
| 英文摘要: |
| Objective To investigate the relationship between red blood cell distribution width (RDW) on admission and perioperative changes and prognosis in elderly hip fracture patients.Methods The medical records of elderly patients who underwent surgicaltreatment of hip fracture at the Affiliated Hospital of Xuzhou Medical University from January 2018 to March 2020 were retrospectivelycollected, and information such as age, gender, body mass index (BMI), Charlson comorbidity index (CCI), type of fracture, admission RDW, and perioperative ΔRDW (the highest postoperative RDW and admission RDW difference) were collected. The risk factors associated with patient mortality were analyzed by LASSO regression and multivariate Cox regression.Results Of the 650 patients, 264were excluded according to exclusion criteria, and a total of 386 patients were finally included in the analysis. Patients in this cohorthad a 1-year postoperative mortality rate of 10.36% (40/386), a 2-year mortality rate of 16.06% (62/386), a 4-year mortality rate of 23.58% (91/386), and a follow-up mortality rate of 26.17% (101/386). LASSO regression analysis showed that age, CCI, admission hemoglobin, albumin, RDW, and ΔRDW, the six variables, were the characteristic variables affecting mortality in elderly patients undergoing hip fracture surgery; the results of the multivariate Cox regression analysis showed age 75-<85 [HR=2.17, 95%CI:(1.27,3.73),P= 0.004], age ≥85 [HR=3.73,95%CI:(2.11,6.62), P<0.00], CCI≥2 [HR=3.58, 95%CI:(2.15,5.95),P<0.001], admission RDW>13.55% [HR= 1.61,95%CI:(1.07,2.41), P=0.022], and ΔRDW>0.89% [HR=3.10,95%CI:(2.00,4.79),P<0.001] were risk factors for mortality in elderly patients undergoing hip fracture surgery.Conclusion Age≥75 years, CCI≥2 points, admission RDW>13.55%, and ΔRDW>0.89% areindependent risk factors for mortality in elderly patients undergoing hip fracture surgery. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
