张翼飞,杨海峰,林俊杰,等.一波三折的非霍奇金淋巴瘤相关肾损害[J].安徽医药,2024,28(12):2381-2385. |
一波三折的非霍奇金淋巴瘤相关肾损害 |
Twists and turns of non-Hodgkin's lymphoma-associated renal damage |
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DOI:10.3969/j.issn.1009-6469.2024.12.010 |
中文关键词: 淋巴瘤,非霍奇金 肾小球肾炎,膜性 新月体肾炎 肿瘤相关肾损害 |
英文关键词: Lymphoma, non-Hodgkin Glomerulonephritis, membranous Crescentic nephritis Tumor-related renal damage |
基金项目:国家自然科学基金资助项目( 82104779);省部共建中医湿证国家重点实验室开放课题( SZ2021KF03);广东省中医药局科研项目( 20232051);广东省中医院张大宁学术经验传承工作室(中医二院〔 2018〕102号) |
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中文摘要: |
目的分享并探讨诊断困难的非霍奇金淋巴瘤相关肾损害的诊疗经验。方法分享广州中医药大学第二附属医院 2019年 12月收治的 1例非霍奇金淋巴瘤相关肾损害病人的诊疗经过和诊断过程。结果第 1阶段,病人表现为肾病综合征,于外院行肾穿刺活检诊断为膜性肾病 Ⅰ期、冷球蛋白血症肾损害待排。第 2阶段,病人因急性肾损伤入住广州中医药大学第二附属医院,行肾穿刺活检诊断为膜性肾病 Ⅱ期伴新月体肾小球肾炎。第 3阶段,病人因左眼眶肿物,行活检后诊断为非霍奇金淋巴瘤。第 4阶段,病人因腹膜炎入院,后病情缓解,摆脱血液透析和腹膜透析。随着化疗肿瘤及肾病的缓解,考虑非霍奇金淋巴瘤相关肾损害成立。结论最初诊断膜性肾病的中老年病人,需更频繁地进行恶性肿瘤筛查。 |
英文摘要: |
Objective To share and discuss the diagnosis and treatment experience of non-Hodgkin's lymphoma-related renal dam-age with diagnostic difficulties.Methods The diagnosis and treatment experience and diagnostic process were shared of a patient with non-Hodgkin's lymphoma-related renal damage admitted to the The Second Affiliated Hospital of Guangzhou University of ChineseMedicine in December 2019.Results In the first stage, the patient presented with nephrotic syndrome and was diagnosed with mem-branous nephropathy stage Ⅰ and cryoglobulinemia renal damage to be drained by renal puncture biopsy in another hospital. In thesecond stage, the patient was admitted to The Second Affiliated Hospital of Guangzhou University of Chinese Medicine for acute kidneyinjury, underwent renal puncture biopsy and was diagnosed with membranous nephropathy stage Ⅱ with crescentic glomerulonephritis.In the third stage, the patient was diagnosed with non-Hodgkin's lymphoma after performing biopsy for left orbital swelling. In thefourth stage, the patient was admitted to hospital because of peritonitis, and then his condition was relieved, and he got rid of hemodialy-sis and peritoneal dialysis. The remission of tumor and the renal disease with chemotherapy suggested a diagnosis of non-Hodgkin's lymphoma related renal damage. Conclusion Middle-aged and elderly patients initially diagnosed with membranous nephropathy need to be screened more frequently for malignancy. |
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