| 颜谈,张艳,王国防,等.以手口综合征为唯一临床表现的脑梗死 4例临床分析并文献复习[J].安徽医药,2025,29(1):166-169. |
| 以手口综合征为唯一临床表现的脑梗死 4例临床分析并文献复习 |
| Clinical analysis of 4 cases of cerebral infarction with cheiro-oral syndrome as the only clinical manifestation and literature review |
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| DOI：10.3969/j.issn.1009-6469.2025.01.034 |
| 中文关键词: 脑梗死 手口综合征 临床特点 危险因素 治疗 预后 |
| 英文关键词: Cerebral infarction Cheiro-oral syndrome Clinical features Risk factors Treatment Prognosis |
| 基金项目:安徽医科大学校科研基金项目( 2022xjk089) |
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| 中文摘要: |
| 目的分析 4例以手口综合征为唯一临床表现的脑梗死的疾病特点，提高大家对该综合征的认识，避免漏诊、误诊。方法回顾性总结于 2021年 2月至 2022年 11月阜阳市人民医院收治的 4例以手口综合征为唯一临床表现的脑梗死病人的人口学信息、既往史、临床表现、入院时美国国立卫生研究院卒中量表( NIHSS)评分、缺血性脑卒中病因学分类标准( TOAST)分型、头颅磁共振成像( MRI)所示病变部位、头颈部血管成像、治疗方式及长期预后等资料。结果 4例病人均存在至少 1种脑梗死高危因素，均表现为同侧口周手部麻木症状，均为腔隙性脑梗死且均为轻型卒中，头颈部血管壁存在斑块或狭窄，给予抗栓、调脂固斑等治疗， 2例长期预后留有感觉障碍后遗症， 2例无任何后遗症。结论手口综合征最常见于脑梗死病人，该类型脑梗死与其他类型的脑梗死危险因素、 TOAST分型、治疗及预后方面存在共性，然而局限性的手口麻木为其特有临床表现。 |
| 英文摘要: |
| Objective To analyze the characteristics of 4 cases of cerebral infarction with cheiro-oral syndrome as the only clinicalmanifestation, so as to improve understannding of the syndrome and avoid underdiagnosis and misdiagnosis.Methods The demograph-ic information, previous history, clinical manifestations, NIHSS score on admission, TOAST etiological classification, lesion sites shownin magnetic resonance imaging, head and neck angiography, treatment methods and long-term prognosis of 4 cerebral infarction pa-tients with cheiro-oral syndrome as the only clinical manifestation admitted to Fuyang People's Hospital from February 2021 to Novem-ber 2022 were retrospectively summarized.Results All the 4 patients had at least one risk factor for cerebral infarction, symptoms ofipsilateral perioral and hand numbness, lacunar cerebral infarction and mild stroke, with plaque or stenosis in the vascular wall of thehead and neck, and were treated with anti-thrombolysis and lipid-controlling plaque fixation. Two cases had sequelae of sensory distur-bance in the long term prognosis, and 2 cases had no sequelae.Conclusions Cheiro-oral syndrome is most commonly seen in patientswith cerebral infarction. There are similarities between this type of cerebral infarction and other types of cerebral infarction in terms ofrisk factors, TOAST classification, treatment and prognosis. However, limited cheiro-oral numbness is its unique clinical manifestation. |
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