| 李桂涛,赵永,朱影,等.连续性血液净化在儿童危重症疾病的应用进展[J].安徽医药,2025,29(2):233-237. |
| 连续性血液净化在儿童危重症疾病的应用进展 |
| Advances in the application of continuous blood purification in critically ill children |
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| DOI：10.3969/j.issn.1009-6469.2025.02.004 |
| 中文关键词: 连续性血液净化 危重症 儿童 |
| 英文关键词: Continuous blood purification Critical illness Children |
| 基金项目:中国红十字基金医学赋能 -领航菁英科研项目( XM-HR-YXFN-2021-05-24)；阜阳市卫生健康委员会科研立项课题( FY2019-050) |
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| 摘要点击次数: 878 |
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| 中文摘要: |
| 连续性血液净化( CBP)技术是一种发展迅速的新兴技术，是儿童重症监护室治疗危重症病儿的一个有效手段，广泛应用于脓毒性血症、 DIC、肝肾功能衰竭、肺脑水肿、急性胰腺炎、遗传代谢病、凝血功能异常及多器官功能障碍等疾病的儿童危重症疾病中。 CBP常用模式是连续静脉 -静脉血液净化模式，包括连续性静脉 -静脉血液透析、连续性静脉 -静脉血液滤过、连续性静脉 -静脉血液透析滤过、脉冲式高容量血液滤过等，常见的并发症有凝血功能异常、出血、血栓、低血糖、过敏及电解质紊乱等。与成人相比，由于儿童病理生理特点、病种不同及设备要求，儿童 CBP要求更高。目前 CBP在危重症疾病的应用中融入了更多的重症思维和重症理念，使之越来越好地救治危重病人。 |
| 英文摘要: |
| Continuous blood purification (CBP) technique is a rapidly developed new technology and an effective means for the treat-ment of critically ill children in pediatric intensive care unit (PICU). CBP is widely used in the treatment of critical illness in childrensuch as septicemia, DIC, liver and renal failure, pulmonary and cerebral edema, acute pancreatitis, inherited metabolic diseases (IMD),coagulant function abnormality and multiple organ dysfunction syndrome (MODS). The common mode of CBP is continuous venous-ve-nous blood purification, including continuous venous-venous hemodialysis (CVVHD), continuous venous-venous hemofiltration (CV-VH) , continuous venous-venous hemodiafiltration (CVVHDF), pulsed high volume hemofiltration (PHVHF). Common complications in-clude coagulopathy, hemorrhage, thrombosis, hypoglycemia, allergy and electrolyte disorder, etc. Compared with adults, children havehigher CBP requirements due to their different pathophysiological features, diseases and equipment requirements. At present, CBP in-corporates more critical thinking and concepts into its application to the treatment of critical diseases, making it better and better forthe treatment of critically ill patients. |
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