| 吴国良,朱嘉俊,赵龙,等.瓣环与左室流出道椭圆率比值及瓣环离心指数对经导管主动脉瓣置换术治疗的主动脉瓣狭窄病人围术期预后的影响[J].安徽医药,2025,29(2):274-279. |
| 瓣环与左室流出道椭圆率比值及瓣环离心指数对经导管主动脉瓣置换术治疗的主动脉瓣狭窄病人围术期预后的影响 |
| Effect of valvular annulus to left ventricular outflow tract ellipticity ratio and valvular annulus centrifugal index on perioperative prognosis of AVS patients undergoing TAVR |
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| DOI：10.3969/j.issn.1009-6469.2025.02.012 |
| 中文关键词: 主动脉瓣狭窄 经导管主动脉瓣置换术 围术期 椭圆率比值 离心指数 |
| 英文关键词: Aortic valve stenosis Transcatheter aortic valve replacement Perioperative prognosis Ellipticity ratio Centrifugal index |
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| 中文摘要: |
| 目的探讨主动脉根部因素［瓣环与左室流出道(LVOT)椭圆率比值、瓣环离心指数］对经导管主动脉瓣置换术(TAVR)治疗的主动脉瓣狭窄( AVS)病人围术期预后的影响。方法选取 2016年 1月至 2022年 5月在新疆医科大学第一附属医院行 TAVR治疗的 AVS病人 110例，根据病人瓣环离心指数与瓣环形态的关系，分为离心指数 <0.1组 65例及离心指数 ≥0.1组 45例，同时根据病人瓣环与 LVOT形态的相似程度将病人分为瓣环与 LVOT椭圆率比值 >1组 43例及椭圆率比值 ≤1组 67例，分别比较瓣环离心指数、瓣环与 LVOT椭圆率比值对病人围手期预后的影响。结果不同瓣环离心指数的 AVS病人围术期的中 /重度瓣周漏率(球囊后扩之前)(15.4%比 46.7%，P<0.001)及新发传导阻滞率( 32.3%比 53.3%，P<0.05)、不同瓣环与 LVOT椭圆率比值的 AVS病人围术期的新发传导阻滞率( 53.5%比 32.8%，P<0.05)差异有统计学意义。结论瓣环与 LVOT椭圆率比值 >1的 TAVR病人有较高的围术期传导阻滞发生率，瓣环离心指数 <0.1的 TAVR病人有较低的围术期传导阻滞发生率及中 /重度瓣周漏率。 |
| 英文摘要: |
| Objective To analyze the effect of aortic root factors (valvular annulus to left ventricular outflow tract (LVOT) ellipticityratio, valvular centrifugation index) on perioperative prognosis of aortic valve stenosis (AVS) patients undergoing transcatheter aorticvalve replacement (TAVR).Methods Retrospective analysis was performed on AVS patients who underwent TAVR (110 cases) in TheFirst Affiliated Hospital of Xinjiang Medical University from January 2016 to May 2022. According to the relationship between the flapring centrifugation index and flap ring morphology, the patients were assigned into a group with a centrifugation index <0.1 (n=65) and a group with a centrifugation index≥0.1 (n=45). Meahwhile, patients were assigned into valvular annulus to LVOT ellipticity ratio >1 group (n=43) and ≤1 group (n=67) according to the similarity of valvular annulus to LVOT morphology. The effects of valvular centrifu-gation index and valvular annulus to LVOT ellipticity ratio on perioperative prognosis were compared.Results Significant differences were found in perioperative rates of moderate/severe perivalvular leakage (15.4% vs. 46.7%, P<0.001) (before post-balloon expansion) and new block (32.3% vs. 53.3%, P<0.05) in AVS patients with different valvular centrifugation indices, and the perioperative rate ofnew block in AVS patients with different valvular annulus to LVOT ellipticity ratio (53.5% vs. 32.8%, P<0.05).Conclusion The inci-dence of perioperative block was higher in TAVR patients with valvular annulus to LVOT ellipticity ratio>1, and the incidences of peri-operative block and moderate/severe perivalvular leakage were lower in TAVR patients with valvular centrifugation index <0.1. |
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