| 蒋鹤松,牛晓兵.经会阴前列腺穿刺术后发热相关危险因素分析[J].安徽医药,2025,29(2):384-387. |
| 经会阴前列腺穿刺术后发热相关危险因素分析 |
| Risk factors for fever after the transperineal prostate biopsy |
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| DOI：10.3969/j.issn.1009-6469.2025.02.035 |
| 中文关键词: 前列腺穿刺活检术 会阴 发热 并发症 危险因素 |
| 英文关键词: Prostate needle biopsy Perineum Fever Complications Risk factors |
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| 中文摘要: |
| 目的探讨经会阴前列腺穿刺术后发热特点及其相关危险因素。方法回顾性分析 2018年 1月至 2020年 12月南京医科大学附属淮安第一医院行经会阴前列腺穿刺术后发热与无发热病人临床、影像及病理资料。记录发热病人临床特点， logis-tic回归分析前列腺穿刺后发热的影响因素。结果 343例病人有 24例病人出现穿刺后发热，发热病人尿白细胞及细菌数正常、血培养或尿培养均阴性。通过单因素和多因素分析发现前列腺体积 >60 mL［OR=5.87，95%CI:(1.34，12.98)］、穿刺前因尿潴留保留导尿［OR=8.17，95%CI:(1.53，17.35)、 IPSS评分 >20分［OR=63.88，95%CI:(7.08，176.20)］、病理提示前列腺炎症细胞浸润［OR=11.02，95%CI:(1.43，41.91)］是经会阴前列腺穿刺发热的独立危险因素( P<0.05)。结论经会阴前列腺穿刺后发热主要原因为炎症介质释放，而非感染性。其中伴有前列腺体积 >60 mL、穿刺前因尿潴留保留导尿、 IPSS评分 >20分或病理提示前列腺炎症细胞浸润病人行经会阴前列腺穿刺后发热风险较高。 |
| 英文摘要: |
| Objective To evaluate risk factors for fever after the transperineal prostate biopsy.Methods Clinical, imaging and path-ological data of patients, who underwent transperineal prostate biopsy in The Affiliated Huaian No.1 People's Hospital of Nanjing Medi-cal University during January 2018 and December 2020, were retrospectively analyzed. The clinical characteristics of patients with fe-ver were recorded. Logistic regression was used to analyze the influencing factors for fever after the transperineal prostate biopsy.Re. sults Twenty-four of 343 patients had fever after the transperineal prostate biopsy. The urine white blood cells and bacteria countwere normal, and blood or urine culture results of patients with fever were negative. Univariate and multivariate analyses results showedthat prostate volume >60 mL [OR=5.87, 95%CI:(1.34,12.98)], catheterization before biopsy [OR=8.17, 95%CI:(1.53,17.35)], IPSS score >20 [OR=63.88, 95%CI:(7.08,176.20)], prostatic inflammatory cell infiltration [OR=11.02, 95%CI:(1.43,41.91)] were independent risk factors for fever after transperineal prostate biopsy (P<0.05).Conclusions The main cause of fever after transperineal prostate biopsyis the release of inflammatory mediators, not infection. Patients with prostatic volume >60 mL, retained catheterization due to urosche-sis before biopsy, IPSS score >20 or prostatic inflammatory cell infiltration have a higher risk of fever after transperineal prostate biopsy. |
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