| 祖孝荣,陈锦华.碱剩余在缺血性脑卒中的研究进展[J].安徽医药,待发表. |
| 碱剩余在缺血性脑卒中的研究进展 |
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| 投稿时间：2025-04-11 录用日期：2025-04-29 |
| DOI： |
| 中文关键词: 碱剩余 缺血性脑卒中 分子机制 预后评估 |
| 英文关键词: |
| 基金项目:2021年度山西省卫生健康科研项目(NO：2021012); |
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| 摘要点击次数: 32 |
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| 中文摘要: |
| 碱剩余(Base Excess, BE)作为评估代谢性酸碱平衡紊乱的关键指标,在缺血性脑卒中的作用日益受到重视。最新研究显示,碱剩余的异常值与患者的氧化应激和炎症反应密切相关,这些反应可影响患者的神经功能缺损程度和预后。此外,碱剩余作为生物标志物的潜力主要体现在其预测缺血性脑卒中患者预后的能力,尤其是在评估疾病严重程度和指导治疗方面。本文就碱剩余在缺血性脑卒中领域的研究进展进行综述,并对碱剩余的未来应用进行展望。 |
| 英文摘要: |
| Base-Excess as a key indicator to evaluate metabolic acid-base balance disorder, the role of base excess in ischemic stroke has been paid more and more attention. Recent studies have revealed that base excess outliers are closely related to oxidative stress and inflammatory responses in patients. These responses can affect the degree of neurological impairment and prognosis. In addition, the potential of base excess as a biomarker is mainly reflected in its ability to predict prognosis in patients with ischemic stroke, especially in assessing disease severity and guiding treatment. This article reviews the research progress of base excess in the field of ischemic stroke, and looks forward to the future application of base excess. |
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