文章摘要
刘晨雨,邓超华,胡维琨.甲状腺相关眼病继发高眼压的发病机制及治疗进展[J].安徽医药,2025,29(5):849-856.
甲状腺相关眼病继发高眼压的发病机制及治疗进展
Pathogenesis and treatment progress of secondary ocular hypertension in thyroid associated ophthalmopathy
  
DOI:10.3969/j.issn.1009-6469.2025.05.001
中文关键词: 甲状腺功能障碍性眼病  Graves眼病  继发性高眼压  继发性青光眼  眼内压
英文关键词: Dysthyroid ophthalmopathy  Graves orbitopathy  Secondary ocular hypertension  Secondary glaucoma  Intraocular pressure
基金项目:国家自然科学基金青年科学基金项目( 82101125);湖北省卫生健康委科研项目( WJ2021M211)
作者单位E-mail
刘晨雨 武汉科技大学附属天佑医院眼科湖北武汉 430064  
邓超华 华中科技大学同济医学院附属同济医院眼科湖北武汉 430064  
胡维琨 武汉科技大学附属天佑医院眼科湖北武汉 430064
华中科技大学同济医学院附属同济医院眼科湖北武汉 430064 
2005tj0557@hust.edu.cn 
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中文摘要:
      甲状腺相关眼病(TAO)是成年人最常见的眼眶病之一。目前关于 TAO的发病机制并不清楚,普遍认为其是一种自身免疫性疾病,临床表现通常有眼睑后退、眼球突出、复视、暴露性角膜炎等,也通常伴随着由多种病理生理机制引起的高眼压,但目前临床医生对 TAO引起的高眼压不够重视,对于继发高眼压的治疗也不够规范。现对 TAO及继发高眼压的流行病学、发病机制和治疗等方面作一概述,为临床诊断和治疗 TAO所致的高眼压提供指导。
英文摘要:
      Thyroid-associated ophthalmopathy (TAO) is one of the most common orbital diseases in adults. At present, the pathogene-sis of TAO is not clear, and it is generally believed that it is an autoimmune disease. Clinical manifestations usually include eyelid re-traction, exophthalmos, diplopia, and exposure keratitis, which are also accompanied by ocular hypertension caused by various patho-logical and physiological mechanisms. However, currently, clinical doctors do not pay enough attention to patients' high intraocularpressure caused by TAO, and the treatment of secondary ocular hypertension is not standardized enough. This article provides an over-view of the epidemiology, pathogenesis, and treatment of thyroid-associated ophthalmopathy and secondary ocular hypertension, so as toguide clinical diagnosis and treatment of high intraocular pressure caused by TAO.
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