| 张玲,吴少君.极早产与超早产儿过快追赶生长时神经发育现状及早期干预的研究[J].安徽医药,待发表. |
| 极早产与超早产儿过快追赶生长时神经发育现状及早期干预的研究 |
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| 投稿时间：2025-05-06 录用日期：2025-06-11 |
| DOI： |
| 中文关键词: 极早/超早产儿 追赶生长 神经发育 早期干预 |
| 英文关键词: |
| 基金项目:科学技术局科研课题(课题标编号:202301A262) |
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| 摘要点击次数: 44 |
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| 中文摘要: |
| 【】 目的:探究极早产与超早产儿过快追赶生长时神经发育现状及早期干预。方法:选取河北省秦皇岛市妇幼保健院2019年1月至2024年1月期间就诊的极早/超早产儿130例纳入研究对象,基于孕周分为极早产组和超早产儿组,每组各65例。在矫正年龄40周,矫正年龄3、6、12、24月龄,矫正年龄36月龄进行生长发育监测,体检频率为出院后6月龄内1次/月,6~12月龄1次/2个月,1~3岁1次/3个月,并对其体格发育进行评估,神经发育采用gesell发育量表、智力发育指数(Mental developmental index,MDI)、精神运动发育指数(Psy－chomotor developmental index,PDI)、神经发育损害情况(Neurdevelopmental impair-ment,NDI)进行评估。结果:干预后极早产儿组其整体体格发育情况优于超早产儿组(P＜0.05)；经干预两组早产儿GDS评分较前均有提升,但极早产儿的GDS评分整体优于超早产儿(P＜0.05)；干预后两组早产儿 MDI与PDI评分较前均有提升,但极早产儿的 MDI与PDI评分整体优于超早产儿(P＜0.05)；极早产儿组NDI概率低于超早产儿组(P＜0.05)。结论:过快追赶生长一定程度上有利于极早产与超早产儿神经发育,改善预后。 |
| 英文摘要: |
| Objective: Explore the current status of neural development and early intervention during rapid catch-up growth in extremely premature and ultra premature infants. Methods: 130 extremely early/ultra preterm infants who visited Qinhuangdao Maternal and Child Health Hospital in Hebei Province from January 2019 to January 2024 were selected as the study subjects. They were divided into extremely preterm group and ultra preterm group based on gestational age, with 65 cases in each group. At the correction age of 40 weeks, 3, 6, 12, 24 months, and 36 months, growth and development monitoring was conducted. The frequency of physical examinations was 1 time/month within 6 months after discharge, 1 time/2 months between 6-12 months, and 1 time/3 months between 1-3 years. Physical development was evaluated using the Gesell Development Scale and Mental Development Index (MDI) Psychomotor developmental index (PDI) and neurodevelopmental impairment (NDI) were evaluated. Results: After intervention, the overall physical development of the extremely premature group was better than that of the ultra premature group (P<0.05); After intervention, the GDS scores of both groups of premature infants improved compared to before, but the GDS scores of extremely premature infants were overall better than those of ultra premature infants (P<0.05); After intervention, the MDI and PDI scores of both groups of premature infants improved compared to before, but the MDI and PDI scores of extremely premature infants were overall better than those of ultra premature infants (P<0.05); The probability of NDI in the extremely premature group was lower than that in the ultra premature group (P<0.05).Coclusion: Rapid catch-up growth to a certain extent is beneficial for the neural development of extremely premature and ultra premature infants, and improves prognosis. |
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