| In developed and developing countries, the problem of aging is becoming more serious. Aging immune systems struggle tocombat bacterial invasions, leading to increased drug-resistant bacterial infections and chronic non-healing wounds. Traditional antibi-otics fail to address these challenges, prompting global efforts to explore novel antimicrobial strategies. Graphene-based materials have emerged as promising antibacterial agents, with graphene composites (nanomaterials, chitosan, curcumin, quaternary ammonium salts,polydopamine) showing clinical potential. This paper focuses on the antibacterial mechanism of graphene materials in the treatment ofdrug-resistant bacteria on wound surface, and analyzes the research progress of graphene combined with nanomaterials, chitosan, cur‐cumin, quaternary ammonium salt, polydopamine, etc., and we have summarized the current problems and provided guidance on the fu-ture development direction, with the aim of enabling readers to have a more comprehensive and systematic understanding of the gra-phene family. |
