| Objective To investigate the magnetic resonance imaging (MRI) findings of sacroiliac joint lesions in patients with spinalarthritis (SpA) and their correlation with bone metabolic indexes.Methods 98 patients with SpA sacroiliac joint lesions admitted toHebei PetroChina Central Hospital from February 2021 to February 2023 were selected as the study group. According to Bath Ankylos-ing Spondylitis Disease Activity Index (BASDAI) and laboratory indicators, they were assigned into an active group (n=48) and a stable group (n=50). Healthy individuals who underwent physical examination during the same period were collected as the health group (n= 45). The levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and bone metabolism indicators such as 25-hy-droxyvitamin D (25-OHVD), type Ⅰ collagen carboxy terminal peptide β special sequence (β-CTX), procollagen type Ⅰ N-terminal propeptide (PINP), parathyroid hormone (PTH), and bone Gla protein were detected. The bilateral sacroiliac joints of the study subjectswere subjected to routine MRI scans, 3D multi-echo data image combination with water excitation (3D MEDIC-WE) scans, and dynam-ic contrast-enhanced MRI (DCE-MRI) scans, and the thickness of sacroiliac joint cartilage, apparent diffusion coefficient (ADC), en-hancement factor (Fenh), and enhancement slope (Senh) were recorded. The correlations between CRP, ESR, BASDAI scores, and MRI parameters, bone metabolism indicators in patients with SpA sacroiliac joint disease were analyzed.Results The sacroiliac articular cartilage of the health group showed no signs in T1 -weighted imaging (T1WI) and T2 -weighted imaging (T2WI), slightly high banded sig-nal in Turbo inversion recovery magnitude T2 -weighted imaging (TIRM-T2WI), smooth high banded signal in 3D-MEDI-WE, and no ab-normal high signal in DCE-MRI and diffusion-weighted imaging (DWI). In the stable and active groups, the sacroiliac articular cartilage showed non-smooth signal in T1WI and T2WI, uneven signal and unclear edge in TIRM-T2WI, non-smooth, eroded and uneven signals in 3D-MEDI-WE, abnormally high signal or patchy high signal in DWI, and continuous enhancement in DCE-MRI. Compared with the health group, the CRP, ESR, iliac cartilage thickness, ADC, Fenh, Senh, and β -CTX were obviously higher in the active and stablephase groups, while the thickness of sacral cartilage, sacral/iliac cartilage thickness ratio, 25-OHVD, PINP, PTH, and bone Gla protein were obviously lower (P<0.05); compared with the stable phase group, the CRP, ESR, BASDAI scores, iliac cartilage thickness, ADC, Fenh, Senh, and β-CTX in the active phase group were obviously higher, while the thickness of sacral cartilage, sacral/iliac cartilage thickness ratio, 25-OHVD, PINP, PTH, and bone Gla protein were obviously lower (P<0.05); CRP, ESR, BASDAI scores were negative-ly correlated with sacral cartilage thickness (r=.0.46, .0.50, .0.48), sacral/iliac cartilage thickness ratio (r=.0.58, .0.50, .0.48), 25-OHVD (r=.0.45, .0.44, .0.48), PINP (r=.0.46, .0.48, .0.43), PTH (r=.0.53, .0.55, .0.57), and osteocalcin (r=.0.48, .0.48, .0.50), while they were positively correlated with iliac cartilage thickness (r=0.56, 0.52, 0.51), ADC (r=0.49, 0.52, 0.44), Fenh (r=0.52, 0.51, 0.56), Senh (r=0.60, 0.60, 0.61) and β-CTX (r=0.53, 0.57, 0.55) (P<0.05).Conclusions MRI plays an important role in the examina-tion of SpA sacroiliac joint lesions, and changes in serum bone metabolism indicators are closely related to SpA sacroiliac joint lesions.Both have important value in the diagnosis of SpA sacroiliac joint lesions. |
