| 江福昌.肺超声B线评分对COPD患者新发心衰风险的预测价值[J].安徽医药,待发表. |
| 肺超声B线评分对COPD患者新发心衰风险的预测价值 |
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| 投稿时间：2025-07-04 录用日期：2025-08-11 |
| DOI： |
| 中文关键词: 肺超声B线评分 慢性阻塞性肺疾病 心衰 预测 |
| 英文关键词: |
| 基金项目:梅州市医药卫生科研课题(2024-B-100) |
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| 中文摘要: |
| 目的 探讨肺超声B线评分对慢性阻塞性肺疾病(COPD)患者新发心力衰竭(HF)风险的预测价值。方法? 选取2023年1月至2024年12月本院收治的COPD患者154例作为研究对象,以是否发生HF为终点事件分为HF组(n=46)和非HF组(n=108),对比两组一般资料、B型钠尿肽(BNP)、左室射血分数(LVEF)及肺部超声B线等资料,采用多因素Logistic回归分析COPD患者新发HF的影响因素,并采用接收者操作特征曲线(ROC)评估相关因素的预测价值。结果? HF组冠心病占比高于非HF组(P<0.05)；HF组BNP水平及肺部超声B线评分较非HF组高,LVEF水平较非HF组低(P<0.05)；多因素Logistic回归分析显示:合并冠心病(OR=4.589,95%CI1.436~14.668)、BNP(OR=1.001,95%CI1.000~1.003)、肺超声B线评分(OR=2.048,95%CI1.583~2.650)为COPD患者新发HF的危险因素,LVEF(OR=0.891,95%CI0.827~0.960)为COPD患者新发HF的保护因素(P<0.05)；ROC曲线显示,肺部超声B线评分预测COPD患者新发心衰的AUC为0.896(95%CI0.836~0.939),特异度为95.37%,敏感度为71.74%,最佳截断值为14分,以最佳截断值分组,结果显示,>14分的患者HF发生率73.92%(34/46)较<14分患者HF发生率26.08%(12/46)高(P<0.05)。结论 肺超声B线评分对COPD患者新发HF风险具有较高的预测价值,可为COPD患者心功能监测提供新策略。 |
| 英文摘要: |
| Objective To investigate the predictive value of lung ultrasound B-ray score on the risk of new-onset heart failure (HF) in patients with chronic obstructive pulmonary disease (COPD).Methods 154 COPD patients admitted to our hospital from January 2023 to December 2024 were selected as the study objects, divided into HF group (n=46) and n=108), comparing the general data Brain natriuretic peptidel? (BNP), left ventricular ejection fraction (LVEF) and pulmonary ultrasound B, and the influencing factors of new HF in COPD patients were analyzed by multifactor Logistic regression, and the receiver operating characteristic curve (ROC).Results The proportion of coronary heart disease in HF group was higher than that in non-HF group (P <0.05); Higher BNP levels and lung ultrasound B scores in the HF group than in the non-HF group, The LVEF level was lower than that in the non-HF group (P <0.05); Multivariate Logistic regression analysis showed that: combined coronary heart disease (OR = 4.589, 95%CI1.436~14.668), BNP(OR=1.001, 95%CI1.000~1.003), lung ultrasound B-ray score (OR = 2.048 95% CI1.583~2.650) as risk factors for new-onset HF in COPD patients, LVEF(OR=0.891, 95%CI0.827~0.960) was a protective factor for new HF in COPD patients (P <0.05); The ROC curve shows that, The AUC of pulmonary ultrasound B-ray score predicting new heart failure in COPD patients was 0.896 (95% CI 0.712 to 0.847), The specificity was 95.37%, A sensitivity of 71.74%, The optimal cutoff value was 14 points, Group with the optimal cut-off value, result display, The incidence of HF in patients with> 14 points was 73.92% (34 / 46) higher than the incidence of HF in patients with <14 points was 26.08% (12 / 46) in patients with <14 points (P <0.05).Conclusions Lung ultrasound B-ray score has a high predictive value for the risk of new HF in COPD patients and can provide a new strategy for monitoring cardiac function in COPD patients. |
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