| 刘志超,温春丽,胡风云.山西省成年睡眠障碍人群睡眠时间与高血压关联研究[J].安徽医药,2025,29(7):1346-1352. |
| 山西省成年睡眠障碍人群睡眠时间与高血压关联研究 |
| LIU Zhichao1,WEN Chunli2,HU Fengyun3 |
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| DOI：10.3969/j.issn.1009-6469.2025.07.016 |
| 中文关键词: 入睡和睡眠障碍 睡眠时间 高血压 相关性 山西省 |
| 英文关键词: Sleep initiation and maintenance disorders Sleep duration Hypertension Correlation Shanxi province |
| 基金项目:山西省重点研发计划(指南)项目( 201603D321060)；吴阶平医学基金会临床科研专项资助基金项目( 320.6750.16129) |
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| 中文摘要: |
| 目的探讨山西省成年睡眠障碍人群睡眠时间与高血压之间的相关性。方法应用 2019年 9月 24日至 2019年 12月 31日山西省重点疾病监测 2019年人群脑卒中筛查数据，纳入研究对象 5 535例，分为睡眠障碍组和正常充足睡眠组，睡眠障碍组睡眠时间分为 <6 h/d、6～<7 h/d、7～<8 h/d、≥8 h/d，通过现场问卷和体格检查收集信息。采用 SPSS 21.0软件对睡眠时间及高血压患病情况进行复杂加权。分别对睡眠时间及高血压采用 χ2检验和 Fisher确切概率法进行人口特征描述，对睡眠时间和高血压关联采用多因素二元 logistic回归模型分析。结果纳入成人 5 535例，其中正常充足睡眠 2 983例( 53.9%)，睡眠障碍人群 2 552例( 46.1%)。其中男性 2 170例( 39.2%)，女性 3 365例( 60.8%)。 18～<45岁 299例( 5.4%)， 45～<60岁 2 668例(48.2%)≥60岁 2 568例( 46.4%)。睡眠障碍人群睡眠时间 <6 h/d、6～<7 h/d、7～<8 h/d、≥8 h/d分别为 2 049、378、86、39例，占 80.3%、 %、3.4%、1.5%。睡眠障碍人群 <6 h/d、6～<7 h/d、7～<8 h/d、≥8 h/d高血压患病率分别为 68.3%、63.0%、52.3%、14.8，48.7%，差异有统计学意义( P<0.05)。睡眠障碍人群与正常睡眠人群在每日累计睡眠时间 7～<8 h上，高血压患病率差异无统计学意义( P>0.05)。多因素二元 logistic回归结果显示，在 2次调整混杂因素后，与睡眠 ～<8 h/d比，睡眠时间 <6 h/d与高血压患病率呈正相关， OR 95%CI为 1.66(1.06，2.61)。进行性别分层后，女性睡眠 <6 h/d与高血压患病率呈正相关 OR 95%CI为 1.94(1.10，3.42)。结论山西省成年睡眠障碍居民每日睡眠时间 <6 h会增加患高血压风险，尤其在女性中患高血压风险更高，应积极采取措施调整生活方式、改善睡眠状态以降低高血压患病风险。 |
| 英文摘要: |
| Objective To investigate the association between sleep duration and hypertension in an adult sleep-disordered population in Shanxi Province.Methods Using data collected from September 24, 2019 to December 31, 2019, on stroke screening in the popula-tion of Shanxi Province Key Disease Surveillance 2019, 5 535 participants in this study were included. The participants were assignedinto two groups: a sleep disorder group and a normal sufficient sleep group. The sleep durations of the sleep disorder group were classi-fied as <6 h/d, 6 to <7 h/d, 7 to <8 h/d, and ≥8 h/d. Information using on-site questionnaires and physical examinations were collected.SPSS 21.0 software was used for complex weighting of sleep duration and hypertension prevalence indicators. Demographic characteris-tics were described using chi-squared test and Fisher's exact test for sleep duration and hypertension, respectively, and the associationbetween sleep duration and hypertension was analyzed using a multifactorial logistic regression model.Results The study included 5535 adults, of whom 2 983 (53.9%) had normal and adequate sleep, while 2 552 (46.1%) had sleep disorders. Of the participants, 2 170(39.2%) were male and 3 365 (60.8%) were female. 299 (5.4%) were 18 to under 45 years old, 2 668 (48.2%) were 45 to under 60 yearsold, and 2 568 (46.4%) were 60 years and older. Among those with sleep disorders, 2 049 (80.3%) slept less than 6 h/d, 378 (14.8%)slept 6 to under 7 h/d, 86 (3.4%) slept 7 to under 8 h/d, and 39 (1.5%) slept 8 h/d or over. The prevalence rates of hypertension in thesleep-disordered population were 68.3% for those sleeping less than 6 h/d, 63.0% for those sleeping 6 to less than 7 h/d, 52.3% forthose sleeping approximately less than 8 h/d, and 48.7% for those sleeping 8 h/d or more. The difference was statistically significant (P< 0.05). There was no statistically significant difference in the prevalence of hypertension between the sleep-disordered population and the normal sufficient sleep population in terms of cumulative sleep time of 7 to under 8 h/d (P>0.05). The results of multivariate binarylogistic regression showed that after adjusting for confounders on two occasions, sleep duration less than 6 h/d was positively associatedwith the prevalence of hypertension compared with sleep duration of 7 to under 8 h/d, with an OR of 1.66 [95%CI: (1.06,2.61)]. After stratification by sex, women who slept less than 6 h/d had a higher prevalence of hypertension with an OR of 1.94 [95%CI: (1.10,3.42)]. Conclusions Adult residents of Shanxi Province with sleep disorders and sleep duration under 6 hours per night are at increased riskof hypertension, especially among women, and thus active measures should be taken to reduce the risk of hypertension by adjusting life-style and improving sleep status. |
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