| 王流云,李琰,王松龄,等.基于丰富环境的靶向性康复训练联合针刺对轻度阿尔茨海默病病人认知功能及睡眠质量的影响[J].安徽医药,2025,29(9):1805-1809. |
| 基于丰富环境的靶向性康复训练联合针刺对轻度阿尔茨海默病病人认知功能及睡眠质量的影响 |
| Effects of targeted rehabilitation training combined with acupuncture based on rich environment on cognitive function and sleep quality of patients with mild AD |
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| DOI：10.3969/j.issn.1009-6469.2025.09.022 |
| 中文关键词: 阿尔茨海默病 丰富环境 靶向性训练 针刺 认知功能 睡眠质量 |
| 英文关键词: Alzheimer's disease Enrich the environment Targeted training Acupuncture Cognitive function Sleep quality |
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| 摘要点击次数: 793 |
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| 中文摘要: |
| 目的探讨基于丰富环境的靶向性康复训练联合针刺对轻度阿尔茨海默病( AD)病人认知功能及睡眠质量的影响。方采用前瞻性随机对照研究，选取 2021年 6月至 2023年 6月于郑州市第九人民医院康复科就诊的 89例轻度 AD病人作为研究法对象。随机数字表法分为联合组( 45例)与对照组(44例)。两组均接受常规西药治疗，对照组在此基础上采用针刺治疗，联合组加用基于丰富环境的靶向性康复训练治疗，连续治疗 3个月。比较两组临床疗效，治疗前后睡眠质量，认知功能、日常生活活动能力，同期记录安全性。结果治疗后，联合组临床疗效明显优于对照组，差异有统计学意义( P<0.05)。治疗后，联合组匹兹堡睡眠质量指数量表( PQSI)评分［( 9.20±2.07)分比( 11.61±1.85)分］、 AD认知功能评定量表( ADAS-cog)［(16.93±1.51)分比( 23.61±2.61)分］低于对照组，差异有统计学意义( P<0.05)。治疗后，联合组阿尔茨海默病协作研究 -日常生活活动问卷(ADCS-ADL)得分高于对照组［(36.93±3.91)分比( 33.84±4.02)分］差异有统计学意义( P<0.05)。结论基于丰富环境的靶向性康复训练联合针刺对 AD病人具有良好的治疗效果，且能改善 AD病，人睡眠质量、认知功能，提高日常生活活动能力。 |
| 英文摘要: |
| Objective To explore the effects of targeted rehabilitation training combined with acupuncture based on a rich environ-ment on cognitive function and sleep quality in patients with mild Alzheimer's disease (AD).Methods A prospective randomized con-trolled study was conducted, selecting 89 mild AD patients who visited the Rehabilitation Department of the Ninth People's Hospital ofZhengzhou from June 2021 to June 2023 as the research subjects. The random number table method was divided into a combinationgroup (45 cases) and a control group (44 cases). Both groups received conventional Western medicine treatment, with the control groupreceiving acupuncture treatment on top of this, and the combination group receiving targeted rehabilitation training based on a rich en-vironment for 3 months of continuous treatment. The clinical efficacy of two groups was compared, including sleep quality, cognitivefunction, and activities of daily living before and after treatment, and safety was recorded during the same period.Results After treat-ment, the clinical efficacy of the combination group was significantly better than that of the control group, and the difference was statis-tically significant(P<0.05).After treatment, the Pittsburgh Sleep Quality Index (PQSI) score [(9.20±2.07) points vs. (11.61±1.85) points] and AD Cognitive Function Assessment Scale (ADAS cog)(ADAS-cog)[(16.93±1.51) points vs. (23.61±2.61) points] in the combinationgroup were lower than those in the control group, and the difference was statistically significant (P<0.05). After treatment, Alzheimer's disease collaborative study daily living activities questionnaire (ADCS-ADL) scored in the combined group was higher than that in the control group [(36.93±3.91) points vs. (33.84±4.02) points],and the difference was statistically significant(P<0.05).Conclusion Target-ed rehabilitation training combined with acupuncture based on a rich environment has a good therapeutic effect on AD patients, andcan improve their sleep quality, cognitive function, and daily living activities. |
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