| 夏金波,张辉,梁涛.精神分裂症病人康复期认知功能情况及其影响因素分析[J].安徽医药,2025,29(10):1981-1984. |
| 精神分裂症病人康复期认知功能情况及其影响因素分析 |
| Analysis of cognitive function and influencing factors in patients with schizophrenia during rehabilitation period |
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| DOI：10.3969/j.issn.1009-6469.2025.10.013 |
| 中文关键词: 精神分裂症 康复期 认知功能 喹硫平 利培酮 阿立哌唑 影响因素 |
| 英文关键词: Schizophrenia Rehabilitation period Cognitive function Quetiapine Risperidone Aripiprazole Influence factor |
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| 中文摘要: |
| 目的分析精神分裂症病人康复期认知功能情况及其影响因素。方法选择铜陵市第三人民医院 2020年 6月至 2022年 4月 136例康复期精神分裂症在院病人；采用华文认知能力量表( CCAS)评估病人认知功能情况，并依据认知功能是否损害分为损害组和未损害组。对比损害组和未损害组精神分裂症病人一般资料、临床特征。采用 logistic多因素回归分析影响精神分裂症病人康复期认知功能的相关因素。结果康复期精神分裂症住院病人认知功能损害发生率为 58.09%。损害组病程、受教育程度为高中及以下占比、家庭总收入 <8 000元/年占比、无医疗报销占比、住院次数、阳性与阴性症状量表( PANSS)总分高于未损害组(P<0.05)，其中， PANSS总分 ≥51分组中，损害组 51(64.56%)例，未损害组 17(29.82%)例，使用喹硫平抗精神病药物占比低于未损害组( P<0.05)。 logistic多因素分析结果显示受教育程度、家庭总收入、抗精神病药物使用种类、住院次数、 PANSS总分是影响精神分裂症病人康复期认知功能的相关因素( P<0.05)。结论精神分裂症病人康复期认知功能损害与受教育程度、家庭总收入、抗精神病药物使用种类、住院次数、 PANSS总分有关。 |
| 英文摘要: |
| Objective To analyze the cognitive function and influencing factors of patients with schizophrenia during rehabilitation. Methods One hundred and thirty-six inpatients with schizophrenia in rehabilitation period in Tongling Third People's Hospital fromJune 2020 to April 2022 were selected. The Chinese Cognitive Ability Scale (CCAS) was used to assess the cognitive function of pa-tients, and they were divided into impaired and non impaired groups based on whether their cognitive function was impaired. The gener-al information and clinical characteristics of schizophrenia patients in the damaged and non damaged groups were compared. Logisticmultiple factor regression analysis was used to analyze the relevant factors affecting cognitive function of schizophrenia patients in therecovery period in Tongling area.Results The incidence of cognitive impairment in hospitalized patients with schizophrenia during re-habilitation was 58.09%. The proportion of patients with high school education or below, total family income < 8 000 yuan/year, no medi-cal reimbursement, number of hospitalizations, positive and negative symptom scale (PANSS) total score in the damaged group werehigher than those in the non damaged groups (P < 0.05). Among the subgroups with a total PANSS score of ≥ 51, 51 (64.56%) were in thedamaged group and 17 (29.82%) were in the non damaged group; the proportion of patients using quetiapine antipsychotic drugs in thedamaged group were lower than that in the non damaged group (P < 0.05). Logistic multifactor analysis showed that education level, totalfamily income, antipsychotic drug use types, number of hospitalizations, and PANSS total score were related factors affecting cognitivefunction of schizophrenic patients during rehabilitation (P < 0.05).Conclusion The cognitive impairment of schizophrenic patients dur-ing rehabilitation is related to their educational level, total family income, antipsychotic drug use, number of hospital stays, and PANSSscore. |
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