| 郭旻晞,朱炳喜.基于 qSOFA及 NLR的列线图模型对重症急性胰腺炎的预测价值[J].安徽医药,2025,29(10):2003-2007. |
| 基于 qSOFA及 NLR的列线图模型对重症急性胰腺炎的预测价值 |
| Predictive value of a nomogram model based on qSOFA,neutrophil to lymphocyte ratio for the prognosis of severe acute pancreatitis |
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| DOI：10.3969/j.issn.1009-6469.2025.10.018 |
| 中文关键词: 重症急性胰腺炎 中性粒细胞与淋巴细胞比值 快速序贯器官衰竭评分 列线图 预测 程度，于入， |
| 英文关键词: Severe acute pancreatitis Neutrophil to lymphocyte ratio Quick sequential organ failure assessment Nomogram Prediction |
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| 中文摘要: |
| 目的探讨快速序贯器官衰竭评分(qSOFA)联合中性粒细胞与淋巴细胞比值( NLR)对重症急性胰腺炎(SAP)的预测价值。方法回顾性分析徐州医科大学附属医院 2021年 9月至 2022年 10月收治的 208例急性胰腺炎病人的临床资料，分为非重症急性胰腺炎组(非 SAP组)和重症急性胰腺炎组( SAP组)，分类标准基于病情严重程度。所有病人均于入院 24 h内进行血样采集并检测相应血液学指标，并于 24 h内进行 qSOFA与 BISAP评分。比较两组间的临床资料并确定危险因素，本研究中使用 logistic回归分析，同时，绘制受试者操作特征曲线( ROC曲线)，研究 qSOFA与 NLR联合评分在预测 SAP方面的价值。结SAP组的中性粒细胞淋巴细胞比率( NLR)［17.48(11.39，26.65)%］显著高于非 SAP组的 NLR［7.45(4.39，11.41)%］(P< |
| 英文摘要: |
| Objective To assess the predictive capability of the quick sequential organ failure assessment (qSOFA) score in conjunc-tion with neutrophil to lymphocyte ratio (NLR) for severe acute pancreatitis (AP).Methods A retrospective analysis was conducted onthe clinical data of 208 patients with acute pancreatitis who were admitted to the Affiliated Hospital of Xuzhou Medical University fromSeptember 2021 to October 2022. The patients were categorized into the non-severe acute pancreatitis (non-SAP) group and severe acute pancreatitis (SAP) group according to the severity of clinical condition. Blood samples were taken within 24 h after admission andthe relevant hematological parameters were measured. The qSOFA and BISAP scores were assessed within 24 h. Comparison of variousindicators was performed between the two groups to determine the risk factors. Logistic regression analysis was employed in this study.Meanwhile, the receiver operating characteristic curve (ROC curve) was generated to assess the predictive value of NLR combined withqSOFA score (referred to as NqSOFA) for SAP.Results The NLR scores [17.48 (11.39, 26.65) %] in the SAP group were significantly higher than those in the non-SAP group [7.45 (4.39, 11.41) %] (P < 0.05). Multivariate regression analysis results indicated that highNLR and qSOFA scores were risk factors for SAP. The areas under the curve (AUC) of NqSOFA score and bedside index of severity ofacute pancreatitis(BISAP) for predicting SAP were 0.89 (P<0.001), 0.82 (P<0.001), with the sensitivities of 92.1% 82.4%, and the spec-ificities of 94.7%, 50.6%.Conclusion NqSOFA score for predicting SAP has relatively high predictive value and sensitivity, whichcan be used to predict SAP within 24 h after admission and provide guidance for early treatment. |
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