文章摘要
赵文彬,梅蓉.间充质干细胞移植治疗多种皮肤病的研究进展[J].安徽医药,2026,30(1):46-49.
间充质干细胞移植治疗多种皮肤病的研究进展
Research progress of mesenchymal stem cell transplantation in treating various skin diseases
  
DOI:10.3969/j.issn.1009-6469.2026.01.010
中文关键词: 间质干细胞移植  硬皮病  伤口愈合  皮肤溃疡  白癜风
英文关键词: Mesenchymal stem cell transplantation  Scleroderma  Wound healing  Skin ulc  Vitiligo
基金项目:
作者单位E-mail
赵文彬 四川大学华西医院皮肤性病科,四川成都 610041  
梅蓉 四川大学华西医院皮肤性病科,四川成都 610041 yuvmd78@163.com 
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中文摘要:
      间充质干细胞( MSCs)是一种来源广泛、容易获得和保存的多能干细胞,能够利用简便的方式在体外进行培养,具有自我修复和多向分化的能力。 MSCs移植后引发的免疫排斥反应较弱,所以在细胞疗法领域应用广泛,并展现出显著的临床优势。伤口愈合、皮肤溃疡、硬性皮肤病、白癜风以及炎症性皮肤病是临床上常见的皮肤疾病,治疗困难且对于病人的影响较大, MSCs在系统性皮肤病的治疗中具有较高的应用价值,因此,该研究对 MSCs治疗多种皮肤病的研究进展进行分析。
英文摘要:
      Mesenchymal stem cells (MSCs) are pluripotent stem cells from a wide range of sources, which are easy to obtain and pre-serve, and can be cultured in vitro in a simple way. These cells have the ability of self-repair and multidirectional differentiation. Due tothe weak immune rejection response triggered by MSC transplantation, they are widely applied in the field of cell therapy and demon-strate significant clinical advantages. Wound healing, skin ulcers, rigid dermatosis, vitiligo and inflammatory dermatosis are commonskin diseases in clinical practice, which are difficult to treat and have a great impact on patients. MSCs have high application value inthe treatment of systemic dermatology. Therefore, this paper analyzes the research progress of MSCs in the treatment of various skin dis-eases.
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