| 秦泽辉,叶莉萍,田行瀚.金黄色葡萄球菌血流感染预后的研究进展[J].安徽医药,2026,30(2):236-241. |
| 金黄色葡萄球菌血流感染预后的研究进展 |
| Research progress on prognosis of staphylococcus aureus bloodstream infection |
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| DOI：10.3969/j.issn.1009-6469.2026.02.005 |
| 中文关键词: 金黄色葡萄球菌 血流感染 医院内感染 预后 预测模型 |
| 英文关键词: Staphylococcus aureus Bloodstream infection Hospital infection Prognostic factors Predictive model |
| 基金项目:山东省医药卫生科技发展计划项目( 2019WS281) |
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| 中文摘要: |
| 金黄色葡萄球菌是院内获得性感染的主要病原体之一，当它侵入血液系统时，就会导致金黄色葡萄球菌血流感染(SABI)。 SABI常见的预后相关因素包括性别、是否有基础疾病，与 SABI的预后关系密切；年龄也是影响预后的独立危险因素；感染耐甲氧西林金黄色葡萄球菌( MRSA)病人预后差，而且不同感染部位导致的血流感染预后情况也不同； SABI病人血清白细胞介素 -10值越高病人预后越差；最后病人接受治疗情况等都对病人预后有影响。分析 SABI预后相关因素并建立评估预后的预测模型，可以帮助临床医生制定最佳的治疗方案和监护措施。 |
| 英文摘要: |
| Staphylococcus aureus, especially the methicillin-resistant strain (MRSA), is a leading cause of hospital-acquired infec-tions. When it enters the bloodstream, it leads to Staphylococcus aureus bloodstream infection (SABI), a condition with significant clini-cal implications. Key prognostic factors for SABI include gender, underlying medical conditions, and age, with the latter being an inde-pendent risk factor that significantly affects outcomes. Patients suffering from MRSA-associated SABI typically have a poorer prognosis.Additionally, the site of infection can lead to different prognostic outcomes in SABI cases. Higher serum levels of interleukin-10 in pa-tients are associated with worsening prognoses. The treatment protocols applied are crucial in influencing the overall prognostic out-comes. A thorough analysis of these prognostic factors and the development of predictive models are essential for enabling clinicians todevise optimal treatment strategies and monitoring protocols. |
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