| 骆宇琛,弓清梅.胞外囊泡在急性呼吸窘迫综合征中的研究进展[J].安徽医药,2026,30(3):456-460. |
| 胞外囊泡在急性呼吸窘迫综合征中的研究进展 |
| Research progress of extracellular vesicles in acute respiratory distress syndrome |
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| DOI：10.3969/j.issn.1009-6469.2026.03.007 |
| 中文关键词: 呼吸窘迫综合征，成人 胞外囊泡 生物标志物 间充质干细胞 弥漫性肺泡损伤 |
| 英文关键词: Respiratory distress syndrome, adult Extracellular vesicles Biomarkers Mesenchymal stem cells Diffuse alveo. lar damage |
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| 摘要点击次数: 346 |
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| 中文摘要: |
| 急性呼吸窘迫综合征( ARDS)是由多种原因引起的危及生命的严重疾病，主要的病理特征是透明膜形成和弥漫性肺水肿。近年来，尽管在支持治疗方面进行了许多研究，但目前 ARDS病人的病死率依然居高不下。胞外囊泡( EVs)是细胞间通信的重要载体，它能够发挥维持细胞稳态、清除细胞碎片以及促进细胞间和器官间通信等重要作用。大多数研究证实了 EVs应用于 ARDS的潜力。该文就 EVs在 ARDS发病机制、生物标志物及治疗作用的研究进展进行综述。 |
| 英文摘要: |
| Acute respiratory distress syndrome (ARDS) is a life-threatening severe disease caused by various factors, with hyalinemembrane formation and diffuse pulmonary edema as its main pathological characteristics. Despite of numerous studies on supportivetreatments in recent years, the mortality rate of ARDS patients remains high. Extracellular vesicles (EVs) are vital carriers of intercellu.lar communication, playing important roles in maintaining cellular homeostasis, clearing cellular debris, and promoting intercellularand interorgan communication. Most studies have confirmed the potential of EVs in ARDS. This article reviews the research progress ofEVs in the pathogenesis, biomarkers, and therapeutic effects of ARDS. |
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