| 刘航.合并糖尿病的嗜酸性粒细胞性胃肠炎误诊感染性腹泻并复发1例[J].安徽医药,待发表. |
| 合并糖尿病的嗜酸性粒细胞性胃肠炎误诊感染性腹泻并复发1例 |
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| 投稿时间：2026-04-08 录用日期：2026-06-01 |
| DOI： |
| 中文关键词: 嗜酸性粒细胞性胃肠炎 复发 感染性腹泻 2型糖尿病 误诊 文献复习 |
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| 中文摘要: |
| 目的 报告1例以出血性腹泻为表现的老年嗜酸性粒细胞性胃肠炎（EG）误诊为感染性腹泻、停药后复发的病例，分析其误诊原因及复发相关因素。方法?回顾性分析1例合并2型糖尿病的黏膜型EG患者临床资料并文献复习。结果?该患者老年女性，临床表现主要出血性腹泻，外周血嗜酸性粒细胞比例明显升高，但感染相关指标正常，肠镜病理活检诊断嗜酸性粒细胞性胃肠炎粘膜型，首次行抗过敏治疗，后自行停药复发给予激素补救。随访3个月无复发。结论 对于抗感染治疗无效的腹泻患者，应注意检测外周血嗜酸性粒细胞，及时完成胃肠镜及病理活检；合并糖尿病的老年EG患者应加强血糖管理，关注维持治疗，以降低复发风险。 |
| 英文摘要: |
| Objective?To report a case of eosinophilic gastroenteritis (EG) in an elderly patient initially misdiagnosed with infectious diarrhea due to hemorrhagic diarrhea and subsequently relapsed after treatment discontinuation, and to analyze the causes of misdiagnosis and factors associated with recurrence.Methods?A retrospective analysis was conducted on a patient with mucosal EG complicated by type 2 diabetes mellitus, along with a literature review.Results?The patient was an elderly female whose main clinical manifestation was hemorrhagic diarrhea. Her peripheral eosinophil percentage was markedly elevated, while infection related indices remained normal. EG (mucosal type) was diagnosed by endoscopic biopsy. She initially received anti allergic therapy but relapsed after self discontinuation of the medication and was subsequently treated with corticosteroids. No recurrence was observed during a 3 month follow up.Conclusion?For patients with diarrhea unresponsive to anti infective therapy, peripheral eosinophil count should be examined and timely endoscopy with biopsy is essential. In elderly EG patients with diabetes, optimizing glycemic control and paying attention to maintenance therapy may help reduce the risk of recurrence. |
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