| 把文娟,甘军,李子芃,等.关于寨卡病毒分子流行病学研究进展[J].安徽医药,待发表. |
| 关于寨卡病毒分子流行病学研究进展 |
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| 投稿时间：2026-04-14 录用日期：2026-05-19 |
| DOI： |
| 中文关键词: 寨卡病毒,病原学,宿主免疫,疫苗 |
| 英文关键词: |
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| 摘要点击次数: 106 |
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| 中文摘要: |
| 寨卡病毒是一种主要通过蚊媒传播,还可以通过性接触、母婴垂直以及输血等途径传播的病原体,感染后可引发发热、皮疹、关节痛、结膜炎等症状,严重时可导致先天性寨卡综合征,对全球公共卫生安全构成严重威胁。尽管目前对寨卡病毒的认知水平、监测能力和干预手段均取得一定进展,但仍面临着诸多持续挑战。本文综述了寨卡病毒基因组多样性、宿主免疫、抗病毒药物探索以及疫苗研发四大核心领域的最新研究进展,以期为后续研究提供参考与借鉴。 |
| 英文摘要: |
| Zika virus is a pathogen primarily transmitted by mosquito vectors but also capable of sexual transmission, mother-to-child vertical transmission, and transmission via blood transfusion. Infection may cause symptoms including fever, rash, arthralgia, and conjunctivitis; in severe cases, it can lead to congenital Zika syndrome, posing a serious threat to global public health security. Although understanding of Zika virus, surveillance capabilities, and intervention strategies have advanced to some extent, numerous persistent challenges remain. This review summarizes recent research progress in four core areas—Zika virus genomic diversity, host immune responses, antiviral drug discovery, and vaccine development—to provide reference and insight for future studies. |
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