| 李墨奇,赵亚子,王鑫铭,等.临床药师参与 1例自述基围虾刺伤食指感染发热的白血病病人治疗用药分析[J].安徽医药,2026,30(4):839-842. |
| 临床药师参与 1例自述基围虾刺伤食指感染发热的白血病病人治疗用药分析 |
| A clinical pharmacist participated in a case of a leukemia patient who reported herself was stabbed by shrimp |
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| DOI：10.3969/j.issn.1009-6469.2026.04.040 |
| 中文关键词: 药学服务 急性髓系白血病 发热性中性粒细胞减少 创伤弧菌 药品不良反应 临床药师 |
| 英文关键词: Pharmaceutical services Acute myeloid leukemia Febrile neutropenia Vibrio vulnificus Adverse drug reaction Clinical pharmasist |
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| 中文摘要: |
| 目的对临床药师参与 1例白血病病人自述被基围虾刺伤致右手食指严重感染的病例进行回顾性分析，为临床药师参与临床诊疗活动提供策略。方法病人诊断手皮肤感染、急性髓系白血病，自述基围虾刺伤，外院治疗效果不佳， 2022年 6月 6日入住安徽医科大学第一附属医院高新院区，临床药师基于临床用药情况，聚焦病人病史，明确病人并非创伤弧菌感染且因考虑真菌感染，给予注射用亚胺培南西司他丁钠 +利奈唑胺片 +注射用伏立康唑的给药方案，并识别注射用亚胺培南西司他丁钠的药物不良反应，给予营养治疗的建议，对整个诊疗过程提供临床药学服务。结果该病人经临床药师参与调整感染方案后，感染情况好转，在此期间出现的消化道不良反应、低钾血症、低蛋白血症等情况也进行了对症处理，最终顺利出院。结论临床药师在参与临床治疗的过程中，应积极发挥作用，从多维度思考问题，并给出合理的用药方案。 |
| 英文摘要: |
| Objective To provide strategies for clinical pharmacists to participate in clinical diagnosis and treatment activities by ret-rospectively analyzing a case of leukemia patient who reported herself was stabbed by shrimp and caused a severe infection of the rightindex finger.Methods The patient was diagnosed with hand skin infection and acute myeloid leukemia. She reported a stab injuryfrom shrimp and received ineffective treatment at an external hospital. On June 6, 2022, the patient was admitted to the First AffiliatedHospital of Anhui Medical University High Tech Branch. Based on the clinical medication status and focusing on the patient's medicalhistory, the clinical pharmacist confirmed that the patient was not infected with Vibrio vulnificus and considering fungal infection, pre-scribed a medication regimen consisting of Imipenem and Cilastatin Sodium for Injection, Linezolid Tablets, and Voriconazole for Injec-tion. Meanwhile, the clinical pharmacist identified an adverse drug reaction of Imipenem and Cilastatin Sodium for Injection, providedrecommendations on nutritional therapy, and delivered comprehensive clinical pharmacy services throughout the entire diagnosis andtreatment process.Results After the clinical pharmacist participated in adjusting the anti-infection regimen for the patient, the pa-tient's infectious condition improved. The gastrointestinal adverse reactions, hypokalemia, hypoalbuminemia and other conditions thatoccurred during this period were also given symptomatic treatment, and the patient was ultimately discharged successfully. Conclu. sion In the process of participating in clinical treatment, clinical pharmacists should play an active role, think about problems frommultiple perspectives, and give their own insights. |
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