| 蒋巨峰,李超桐,李婧,等.基于络病理论浅析高血压血管功能障碍中西医机制[J].安徽医药,2026,30(7):1290-1296. |
| 基于络病理论浅析高血压血管功能障碍中西医机制 |
| Research progress in Traditional Chinese and Western Medicine on endothelial dysfunction in hypertension |
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| DOI：10.3969/j.issn.1009-6469.2026.07.004 |
| 中文关键词: 高血压 血管功能障碍 脉络学说 气络学说 中西医结合 |
| 英文关键词: Hypertension Vascular dysfunctions Pulse and collateral doctrine Qi-collateral doctrine Integrative medicine |
| 基金项目:上海市健康科普引领人才能力提升专项( JKKPYL-2022-05)；上海市中医药学会“凯宝”青年医师海派中医传承研究项目( 2023-HPZY-02) |
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| 中文摘要: |
| 高血压已成为影响人类健康的首要病因，而血管功能障碍是导致高血压的主要因素。因此，充分把握血管功能障碍的发生发展机制将成为防治高血压的关键。目前，现代医学针对高血压血管功能障碍已经进行了深入研究，提出了包括钙离子通路、免疫炎症通路、氧化应激通路等机制；传统中医通过不断传承创新，建立“络病理论”，并分化产生“脉络学说”“气络学说”，为中医脉络理论体系指导现代血管疾病的研究开辟了新途径。该研究综述了相关中西医研究进展，以期聚焦热点、把握方向，为高血压血管功能障碍的防治提供参考与借鉴。 |
| 英文摘要: |
| Hypertension has become the leading cause of human health problems, and vascular dysfunction is the main factor leadingto hypertension. Therefore, fully grasping the occurrence and development mechanism of vascular dysfunction will become the key topreventing and treating hypertension. At present, modern medicine has conducted in-depth research on vascular dysfunction in hyper-tension, and put forward mechanisms including calcium ion pathway, immuno-inflammatory pathway, oxidative stress pathway, etc. Tra-ditional Chinese medicine, through continuous inheritance and innovation, has established the "Pulse and Collateral Doctrine", and fur-ther differentiated it into the "Vessel-Collateral Doctrine" and "Qi-Collateral Doctrine", which opens up a new way for the theoreticalsystem of Chinese medicine pulse and collaterals to guide the research of modern vascular diseases. This article reviews the progress ofrelated Chinese and Western medicine research, with a view to focusing on the hot spots, grasping the direction, and providing refer-ence and guidance for the prevention and treatment of hypertensive vascular dysfunction. |
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