| 陈艺,周春明,王玉娟,等.全身振动训练对进行性假肥大性肌营养不良儿童安全性和可行性的研究进展[J].安徽医药,2026,30(9):1743-1748. |
| 全身振动训练对进行性假肥大性肌营养不良儿童安全性和可行性的研究进展 |
| Research progress on the safety and feasibility of whole body vibration training in children with Duchenne muscular dystrophy |
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| DOI：10.3969/j.issn.1009-6469.2026.09.009 |
| 中文关键词: 进行性假肥大性肌营养不良 全身振动 儿童 康复 安全性 可行性 |
| 英文关键词: Duchenne muscular dystrophy Whole body vibration Child Rehabilitation Safety Feasibility |
| 基金项目:广东省高水平医院建设经费深圳市儿童医院临床研究专项( LCYJ2022084) |
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| 中文摘要: |
| 进行性假肥大性肌营养不良( DMD)是一组遗传性肌肉退行性疾病，临床表现为进行性肌无力、关节挛缩，部分病儿会出现继发性骨质疏松、疼痛、心肺功能障碍等合并症。该研究系统探讨全身振动(WBV)训练的作用机制，分析 WBV在 DMD儿童中应用的安全性与临床可行性，并针对不同疾病分期( Vignos分期)进行 WBV训练方案个体化探讨。当前的研究存在样本量小、随访期短等局限，未来需通过多中心临床试验优化振动参数与分层治疗策略，以建立 DMD儿童康复管理的循证方案。 |
| 英文摘要: |
| Duchenne muscular dystrophy (DMD) is a group of hereditary muscle degenerative diseases, clinically characterized by pro.gressive muscle weakness, joint contracture, and some affected children may also develop secondary osteoporosis, pain, and cardiopul.monary dysfunction. This paper systematically explores the mechanism of action of whole body vibration (WBV) training and analyzesthe safety and clinical feasibility of WBV application in children with DMD. Individualized WBV training protocols are discussed fordifferent disease stages (Vignos staging). Current research is limited by small sample sizes and short follow-up periods. Future multi-center clinical trials are needed to optimize vibration parameters and stratified treatment strategies, aiming to establish evidence-based rehabilitation management protocols for children with DMD. |
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