| 郭齐,李萍,许霞,等.血液学指标在小儿重症肺炎支原体肺炎中的诊断价值[J].安徽医药,2026,30(9):1801-1804. |
| 血液学指标在小儿重症肺炎支原体肺炎中的诊断价值 |
| The diagnostic value of hematological indicators in severe mycoplasma pneumoniae pneumonia in children |
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| DOI：10.3969/j.issn.1009-6469.2026.09.019 |
| 中文关键词: 肺炎支原体肺炎 儿童 肺实变 中性粒细胞 乳酸脱氢酶 预测模型 诊断价值 |
| 英文关键词: Mycoplasmal pneumoniae pneumonia Pulmonary consolidation Neutrophil Lactate dehydrogenase Children Predictive model Diagnostic value |
| 基金项目:安徽省高校自然科学研究项目( 2023AH053378) |
| 作者 | 单位 | | 郭齐 | 安徽省第二人民医院儿科,安徽合,肥 230041 | | 李萍 | 安徽理工大学医学院,安徽淮南 232001 | | 许霞 | 安徽省第二人民医院儿科,安徽合,肥 230041 | | 陈洁洁 | 安徽省第二人民医院儿科,安徽合,肥 230041 | | 陈乐园 | 安徽省第二人民医院儿科,安徽合,肥 230041 | | 郭徽 | 合肥市妇幼保健院医务处,安徽合肥 230000 |
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| 中文摘要: |
| 目的探讨血液炎症指标在小儿重症肺炎支原体肺炎( SMPP)中的诊断价值。方法回顾性研究。选取 2023年 7月至 2024年 6月在安徽省第二人民医院接受治疗的 243例肺炎支原体肺炎( MPP)病儿，分为重症组( 96例)和轻症组( 147例)。分析两组基础信息及血液学指标白细胞、中性粒细胞( NEU)、淋巴细胞( LYM)、 C反应蛋白( CRP)、乳酸脱氢酶( LDH)、中性粒细胞与淋巴细胞比值( NLR)水平，并运用二元 logistic回归分析及受试者操作特征曲线( ROC曲线)探讨联合检测在 SMPP诊断中的应用价值。结果重症组肺实变病儿占比［70.8%(68/96)比 11.6%(17/147)］及 NEU［5.07(3.90，7.35)×109/L比 4.18(3.00， 5.94)×109/L］、LDH［271.50(245.00，326.75)U/L比 247.00(223.00，272.00)U/L］、 CRP水平明显高于轻症组( P<0.05)； logistic回归分析显示， NEU、LDH、有肺实变均是 SMPP的危险因素。预测模型 =.6.97+0.21×NEU+0.07×LDH+3.01×肺实变； ROC曲线结果显示， 3项指标联合检测诊断 SMPP的灵敏度、特异度分别为 84.4%、83.7%，AUC为 0.89，诊断效能优于单项检测( P<0.05)。结论 NEU、LDH、肺实变联合检测在 SMPP中具有较高的诊断价值，预测模型为临床 SMPP提供了早期诊断依据。 |
| 英文摘要: |
| Objective To explore the diagnostic value of blood inflammatory indicators in children with severe mycoplasma pneu.moniae pneumonia (SMPP). Methods A retrospective study was conducted. 243 children with mycoplasma pneumoniae pneumonia(MPP) treated at Anhui No.2 Provincial People's Hospital from July 2023 to June 2024 were selected and divided into severe groups(96 cases) and mild groups (147 cases). The basic information and blood indicators of the two groups, including white blood cells(WBC), neutrophils (NEU), lymphocytes (LYM), C-reactive protein (CRP), lactate dehydrogenase (LDH), and the neutrophil-to-lympho.cyte ratio (NLR), were analyzed. Binary logistic regression and the receiver operating characteristic curve (ROC curve) were used to ex.plore the application value of combined detection in the diagnosis of SMPP.Results The proportion of children with pulmonary consol. idation [70.8% (68/96) vs. 11.6% (17/147)] and the levels of NEU [5.07 (3.90, 7.35) ×109/L vs. 4.18 (3.00, 5.94) ×109/L], LDH [271.50 (245.00, 326.75) U/L vs. 247.00 (223.00, 272.00) U/L] and CRP were significantly higher in the severe group than those in the mild group (P < 0.05). Logistic regression analysis identified NEU, LDH, and the presence of pulmonary consolidation as independent riskfactors for SMPP. The derived prediction model was: .6.97+0.21×NEU+0.07×LDH+3.01× pulmonary consolidation. ROC curve analy.sis showed that combining the three indices achieved a sensitivity of 84.4% and a specificity of 83.7% for diagnosing SMPP, with anAUC of 0.89; this diagnostic performance was superior to that achieved with individual biomarker testing (P<0.05).Conclusions Com. bined assessment of NEU, LDH, and pulmonary consolidation offers high diagnostic value for SMPP. The predictive model provides abasis for the early diagnosis of clinical SMPP. |
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