| 鲍八虎,叶育才,陈国荣,等.细胞自噬影响支气管哮喘气道炎症和重塑的研究进展[J].安徽医药,2026,30(10):1909-1913. |
| 细胞自噬影响支气管哮喘气道炎症和重塑的研究进展 |
| Research progress on the impact of cell autophagy on airway inflammation and remodeling in bronchial asthma |
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| DOI：10.3969/j.issn.1009-6469.2026.10.001 |
| 中文关键词: 哮喘 气道炎症 气道重塑 细胞自噬 自噬调节剂 |
| 英文关键词: Asthma Airway inflammation Airway remodeling Cellular autophagy Autophagy regulator |
| 基金项目:甘肃省自然科学基金项目( 21JRIRA074) |
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| 中文摘要: |
| 支气管哮喘是一种常见的呼吸系统疾病，气道炎症和重塑是哮喘的重要发病机制。自噬是指细胞通过内源性机制降解和回收自身的细胞成分，对维持机体稳态具有重要作用。在哮喘发生发展的过程中有着多种细胞参与，研究表明，不同类型的细胞自噬可能通过不同机制来影响哮喘的发生发展。该研究就哮喘发生过程中所涉及的多种细胞自噬进行综述，为探究哮喘的发病机制提供新的思路。 |
| 英文摘要: |
| Bronchial asthma is a common respiratory disease characterized by airway inflammation and remodeling, which are importantmechanisms in its pathogenesis. Autophagy refers to the endogenous process by which cells degrade and recycle their own components,playing a crucial role in maintaining homeostasis in the body. Various cell types are involved in the occurrence and development of asth-ma, and research suggests that autophagy in different cell types may influence the pathogenesis of asthma through diverse mechanisms.This study reviews the autophagy occurring in various cell types involved in the pathogenesis of asthma, providing new perspectives for ex-ploring the underlying mechanisms of the disease. |
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