| 江福昌,黄东雅,王振昌,等.肺超声 B线评分对慢性阻塞性肺疾病病人新发心力衰竭风险的预测价值[J].安徽医药,2026,30(10):2075-2079. |
| 肺超声 B线评分对慢性阻塞性肺疾病病人新发心力衰竭风险的预测价值 |
| Predictive value of lung ultrasound B-line score for the risk of new-onset heart failure in patients with COPD |
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| DOI：10.3969/j.issn.1009-6469.2026.10.032 |
| 中文关键词: 肺疾病，慢性阻塞性 肺超声 B线评分 脑利尿钠肽 心力衰竭 左室射血分数 预测 /4 |
| 英文关键词: Pulmonary disease, chronic obstructive Lung ultrasound B-line score Brain natriuretic peptide Heart failure Left ventricular ejection fraction Prediction |
| 基金项目:梅州市医药卫生科研课题项目( 2024-B-100) |
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| 中文摘要: |
| 目的探讨肺超声 B线评分对慢性阻塞性肺疾病( COPD)病人新发心力衰竭( HF)风险的预测价值。方法回顾性研究。选取 2023年 1月至 2024年 12月梅州市人民医院收治的 COPD病人 154例作为研究对象，以是否发生 HF为终点事件分为 HF组( n=46)和非 HF组( n=108)对比两组一般资料、脑利尿钠肽( BNP)、左室射血分数( LVEF)及肺超声 B线等资料，采用多因素 logistic回归分析 COPD病人新，发 HF的影响因素，并采用受试者操作特征曲线( ROC曲线)评估相关因素的预测价值。结HF组冠心病占比高于非 HF组( P<0.05)； HF组 BNP水平( 360.67±74.66)ng/L及肺超声 B线评分( 15.26±3.63)分较非 HF组(7果.79±2.38)分、(315.30±80.64)ng/L高， LVEF水平较非 HF组低( P<0.05)；多因素 logistic回归分析显示:合并冠心病［ OR=4.589，95%CI:(1.436，14.668)］、 BNP［OR=1.001，95%CI:(1.000，1.003)］、肺超声 B线评分［ OR=2.048，95%CI:(1.583，2.650)］为 COPD病人新发 HF的危险因素， LVEF［OR=0.891，95%CI:(0.827，0.960)］为 COPD病人新发 HF的保护因素( P<0.05)； ROC曲线显示，肺超声 B线评分预测 COPD病人新发 HF的 AUC为 0.896［95%CI:(0.836，0.939)］特异度为 95.37%，灵敏度为 71.74%，最佳截断值为 14分。以最佳截断值分组，结果显示， >14分的病人 HF发生率 73.92%(346)较 <14分病人 HF发生率 26.08%(12/46)高( P<0.05)。结论肺超声 B线评分对 COPD病人新发 HF风险具有较高的预测价值，可为 COPD病人心功能监测提供新策略。 |
| 英文摘要: |
| Objective To investigate the predictive value of lung ultrasound B-line score for the risk of new-onset heart failure (HF) in patients with chronic obstructive pulmonary disease (COPD).Methods Retrospective study. A total of 154 COPD patients admittedto Meizhou People's Hospital from January 2023 to December 2024 were enrolled as the study subjects and divided into an HF group (n =46) and non-HF group (n=108) based on the occurrence of HF as the endpoint event. General data, B-type natriuretic peptide (BNP), left ventricular ejection fraction (LVEF) and lung ultrasound B-line were compared between the two groups. The influencing factors of new-onset HF in COPD patients were identified by multivariate logistic regression, and receiver operating characteristic curve (ROCcurve) was drawn to evaluate the predictive value of relevant factors.Results The proportion of patients with coronary artery disease was higher in the HF group than that in the non-HF group (P<0.05). The HF group had signficantly higher BNP level [(360.67±74.66) ng/L vs. (315.30±80.64) ng/L] and lung ultrasound B-line score [(15.26±3.63)points vs. (7.79±2.38)points], and lower LVEF compared with the non-HF group (P<0.05). Multivariate logistic regression analysis showed that comorbid coronary heart disease [OR=4.589, 95%CI: (1.436, 14.668)], BNP [OR=1.001, 95%CI: (1.000, 1.003)], and lung ultrasound B-line score [OR=2.048, 95%CI: (1.583, 2.650)] were risk factors for new-onset HF in COPD patients, while LVEF [OR=0.891, 95%CI: (0.827, 0.960)] was a protective factor (P <0.05). ROC curve analysis showed that the area under the curve (AUC) of lung ultrasound B-line score for predicting new-onset HF in COPD patients was 0.896 [95%CI: (0.836, 0.939)], with a specificity of 95.37%, and a sensitivity of 71.74%, and the optimal cutoff val-ue was 14 points. Based on this cutoff value for grouping, patients with a B-line score > 14 points had a significantly higher incidence of HF compared with those with a score <14 points [73.92 % (34/46) vs. 26.08 % (12/46), P<0.05].Conclusions Lung ultrasound B-line score has a high predictive value for the risk of new-onset HF in COPD patients, providing a new strategy for monitoring cardiac func-tion in COPD patients. |
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