| 沈凯奇,屈春梅,李韶.纳米复合流体树脂修复前磨牙楔状缺损的疗效及对龈沟液中 ALP、AST的影响[J].安徽医药,2026,30(10):2091-2095. |
| 纳米复合流体树脂修复前磨牙楔状缺损的疗效及对龈沟液中 ALP、AST的影响 |
| Effect of nanocomposite flowable resin in repairing premolars with wedge-shaped defects and the impact on ALP and AST in gingival crevicular fluid |
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| DOI：10.3969/j.issn.1009-6469.2026.10.035 |
| 中文关键词: 牙科修补物修复 前磨牙 楔状缺损 纳米复合流体树脂 碱性磷酸酶 天冬氨酸氨基转移酶 |
| 英文关键词: Dental restoration repair Premolars Wedge-shaped defect Nanocomposite flowable resin Alkaline phospha-tase Aspartate aminotransferase |
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| 中文摘要: |
| 目的探究纳米复合流体树脂修复前磨牙楔状缺损的疗效及对龈沟液中碱性磷酸酶( ALP)和天冬氨酸氨基转移酶(AST)的影响。方法前瞻性研究。采用随机数字表法将平顶山学院附属口腔医院 2023年 6月至 2024年 9月收治的 110例前磨牙楔状缺损病人(共 110颗患牙)分为纳米复合流体树脂组和 FujiⅡLC树脂组，各 55例。 FujiⅡLC树脂组接受 FujiⅡLC树脂改性光固定化玻璃材料修复，纳米复合流体树脂组接受 Z350纳米流体复合树脂修复，比较两组修复效果、 ALP、AST水平、龈缘刺激情况、菌斑附着情况、咀嚼功能以及不良反应。结果纳米复合流体树脂组充填体脱落( 87.27%)、边缘密合性( 83.64%)、色泽协调性( 92.73%)、边缘着色( 89.09%)、继发龋( 94.55%)、牙髓反应( 85.45%)、表面形态修复满意度( 90.91%)均高于 FujiⅡ LC树脂组的 63.64%、65.45%、69.09%、67.27%、67.27%、63.64%、65.45%(P<0.05)，修复 3个月后，纳米复合流体树脂组 ALP、 AST、咀嚼效率、牙齿咬合力分别为( 75.16±11.58)U/L、(725.86±54.15)U/L、(88.46±4.33)%、(138.95±21.58)Ibs均显著高于 Fuji ⅡLC树脂组的( 69.04±10.16)U/L、(633.54±56.71)U/L、(84.07±4.18)%、(124.29±22.72)Ibs(P<0.05)，菌斑指数( PLI)、牙龈指数(GI)、牙龈沟出血指数( SBI)分别为 0.67±0.14、0.91±0.23、1.04±0.18均显著低于 FujiⅡLC树脂组的 0.79±0.16、1.17±0.24、1.28± |
| 英文摘要: |
| Objective To investigate the efficacy of nanocomposite flowable resin in repairing premolars with wedge-shaped defects and its effects on alkaline phosphatase (ALP) and aspartate aminotransferase (AST) in gingival crevicular fluid.Methods Prospective study. Using random number table method, 110 patients with wedge-shaped defective premolars (110 affected teeth) who were admittedto the Pingdingshan College Affiliated Stomatological Hospital from June 2023 to September 2024 were randomly divided into the nano-composite flowable resin group and the FujiⅡLC group, with 55 cases in each group. The FujiⅡLC group received restoration with res-in-modified glass ionomer cement (FujiⅡLC), while the nanocomposite flowable resin group received restoration with Z350 nanocompos-ite flowable resin. The restoration effects, ALP and AST levels, stimulation to gingival margin, plaque attachment, masticatory function,and adverse reactions in the two groups were compared.Results The satisfaction rates with filling material loss, marginal fitness, colorcoordination, edge coloring, secondary caries, pulp response, and restoration of surface morphology in the nanocomposite flowable resingroup (87.27%, 83.64%, 92.73%, 89.09%, 94.55%, 85.45%, and 90.91%) were higher than those in the Fuji Ⅱ LC group (63.64%,65.45%, 69.09%, 67.27%, 67.27%, 63.64%, and 65.45%) (P<0.05). Three months after restoration, ALT level, ASP level, masticatoryefficiency and bite force of the nanocomposite flowable resin group [(75.16±11.58) U/L, (725.86±54.15) U/L, (88.46±4.33) % and(138.95±21.58) Ibs] were significantly higher than those of the FujiⅡLC group [(69.04±10.16) U/L, (633.54±56.71) U/L, (84.07±4.18)%and (124.29±22.72) Ibs] (P<0.05). The plaque index (PLI), gingival index (GI) and sulcus bleeding index (SBI) (0.67±0.14, 0.91±0.23and 1.04±0.18) were significantly lower than those in the FujiⅡLC group (0.79±0.16, 1.17±0.24 and 1.28±0.21) (P<0.05). There was no statistically significant difference in the incidence of complications between the two groups (P>0.05). Conclusions Nanocomposite flowable resin is effective in restoring premolars with wedge-shaped defects. It can significantly improve the levels of ALP and AST ingingival crevicular fluid, alleviate stimulation to gingival margin and plaque attachment, and enhance patients' masticatory function. |
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