| 朱凯媛,蔡 辉.氧化应激致心室重构的研究进展[J].安徽医药,2015,19(9):1633-1636. |
| 氧化应激致心室重构的研究进展 |
| Research Progress on ventricular remodeling induced by oxidative stress |
| 投稿时间：2015-03-23 |
| DOI： |
| 中文关键词: 心室重构 氧化应激 活性氧 抗氧化治疗 |
| 英文关键词: ventricular remodeling oxidative stress reactive oxygen species antioxidant therapy |
| 基金项目: |
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| 中文摘要: |
| 心室重构意味着血管壁中氧化应激水平的提高,当机体受到有害刺激时,氧化和抗氧化之间失衡,导致大量活性氧簇(ROS)的产生,加速心室重构的进展。近年来,新型抗氧化剂成为治疗或预防心室重构的靶点,观察抗氧化剂治疗在心室重构患者的长期应用是当下趋势。该文就氧化应激与心室重构之间的关系及相关药物治疗进行综述。 |
| 英文摘要: |
| Ventricular remodeling means increase of oxidative stress in the vascular wall level.When the body encounters harmful stimuli,the imbalance between oxidation and antioxidation occurs,resulting in a large number of reactive oxygen species andaccelerateingventricular remodeling.Recently,the new antioxidants become the targets of treatment or prevention in ventricular remodeling,therefore,the long-term use of antioxidant therapy tend to be studied among ventricular remodelingpatients.In this article the relationship between oxidative stress and ventricular remodeling and the related drug treatment were reviewed. |
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