文章摘要
苏鸿莉,晋雅凌.胶体液预负荷和晶体液共负荷在预防腰麻剖宫产术中低血压效应的临床疗效对比[J].安徽医药,2015,19(11):2210-2211.
胶体液预负荷和晶体液共负荷在预防腰麻剖宫产术中低血压效应的临床疗效对比
Comparison of the efficacy of hypotension by colloid preload and crystalloidco-load in cesarean section under spinal anesthesia
投稿时间:2015-04-17  
DOI:
中文关键词: 胶体液预负荷  晶体液共负荷  低血压  腰麻剖宫产术
英文关键词: colloid preload, crystalloid co-load, hypotension, cesarean section under spinal anesthesia
基金项目:陕西省卫生科研项目(No 2014-D27)
作者单位
苏鸿莉 延安大学附属医院麻醉科,陕西 延安 716000 
晋雅凌 陕西省第四人民医院妇产科,陕西 西安 710000 
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中文摘要:
      目的 比较胶体液预负荷和晶体液共负荷在预防腰麻剖宫产术中低血压效应的临床疗效。方法 选取腰麻剖宫产术的产妇150例,随机分为胶体液预负荷和晶体液共负荷两组。 胶体液预负荷组在腰麻前15 min 内注射500 mL羟乙基淀粉200/0.5氯化钠注射液;晶体液共负荷组在鞘内注射麻醉时,同时注射1 000 mL 乳酸钠林格注射液进行共负荷, 当产妇有低血压症状时,注射麻黄碱;记录产妇低血压症状发生概率,麻黄碱使用量,以及术中恶心呕吐情况;新生儿通过Apgars评分,脐静脉血气来分析。结果 胶体液预负荷组和晶体液共负荷组在低血压概率分别为46.7% 和45.3%,没有显著性(P>0.05);麻黄碱使用量和产妇术中恶心呕吐情况,新生儿Apgars评分和脐静脉血气指数没有显著性(P>0.05)。结论 在腰麻剖宫产术中,使用500 mL 胶体液预负荷和1 000 mL 晶体液共负荷在预防低血压症状的临床效果相似,二者都只能降低低血压效应发生率,而不能彻底预防血压效应,应该联合其他血管加压药物才能彻底预防腰麻剖宫产术中低血压效应。
英文摘要:
      Objective The study is to compare the efficacy of hypotension by colloid preload and crystalloid co-load in cesarean section under spinal anesthesia. Methods The study took advantage of randomized, double-blind method, and 150 cases for cesarean section under spinal anesthesia were selected, and they were randomly divided into two groups which are colloid preload group and crystalloid co-load group. The pregnancies in the colloid preload group received 500 mL hydroxyethyl starch injection within 15 min before spinal anesthesia; pregnancies in the crystalloid co-load group start intrathecal injection as soon as they were injected with 1000 mL Sodium Acetate Linger's Injection to co-load; when there is hypotension symptoms, pregnancies were injected with ephedrine, respectively; recording probability of maternal hypotension symptoms, ephedrine usage, as well as intraoperative nausea and vomiting during surgery; newborn outcomes were collected by Apgars score and umbilical venous blood gas analyzes. Results The probabilities of hypotension colloid preload group and crystalloid co-load group are 46.7% and 45.3%, respectively, (p>0.05); the dosage of ephedrine, maternal intraoperative nausea and vomiting during surgery, and Apgars score and umbilical venous blood gas index of neonatal between the two groups have no significant difference. Conclusions In cesarean section under spinal anesthesia, the use of 500 mL colloid preload and 1000 mL crystalloid co-load have similar clinical effects in preventing hypotension, both can reduce the incidence of hypotension effect, but they cannot completely prevent hypotension, they should combined with other vasopressors to completely prevent hypotension during s cesarean section under spinal anesthesia.
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