文章摘要
曾玲.细辛脑注射液和多索茶碱联合治疗儿童支气管哮喘急性发作的临床效果[J].安徽医药,2017,21(1):130-132.
细辛脑注射液和多索茶碱联合治疗儿童支气管哮喘急性发作的临床效果
Clinical effect of Asarone injection combined with doxofyline in treatment of children with bronchial asthma in acute attack
投稿时间:2016-07-10  
DOI:
中文关键词: 细辛脑注射液  多索茶碱  支气管哮喘  急性发作
英文关键词: Asarone injection  Doxofylline  Bronchial asthma  Acute attack
基金项目:
作者单位
曾玲 黄冈市中心医院新生儿科,湖北 黄冈 438000 
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中文摘要:
      目的 探讨细辛脑注射液联合多索茶碱治疗儿童支气管哮喘急性发作的临床疗效。方法 选取78例支气管哮喘急性发作患儿选择为研究病例,且采用随机、单盲法分作两组。对照组39例单用多索茶碱治疗,观察组39例采用多索茶碱联合细辛脑注射液治疗,对比临床疗效。结果 观察组有效率为97.44%,与对照组76.92%比较,差异有统计学意义(P<0.05)。观察组患儿咳嗽、喘息、呼吸困难、肺部哮鸣音消失时间及住院时间分别为(3.26±0.71)、(2.19±0.85)、(3.82±0.67)、(4.27±0.96)、(5.74±1.06)d,与对照组比较明显减少,组间比较差异有统计学意义(P<0.05)。两组治疗前肺功能各项指标比较差异均无统计学意义(P>0.05)。观察组患儿治疗后第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、最大呼气流量(PEF)分别为(2.76±0.38)L、(3.07±0.56)L、(3.46±0.51)L·s-1,观察组治疗后与治疗前比较及观察组与对照组比较均差异有统计学意义(P<0.05)。结论 细辛脑注射液联合多索茶碱用于儿童支气管哮喘急性发作的治疗效果显著,能够快速、有效改善患儿症状、体征,缩短住院时间,值得借鉴和推广应用。
英文摘要:
      Objective To investigate the clinical efficacy of asarone injection combined with doxofylline the treatment of acute attack bronchial asthma in children. Methods 78 cases of children with acute bronchial asthma were selected and divided into two groups with the random,single blind method.39 cases in the control group were treated with doxofylline treatment.39 cases in the observation group were treated with doxofylline treatment combined with asarone injection.The clinical efficacy were compared. Results Compared with 76.92 % in the control group,the effective rate of observation group was 97.44 %,which was significantly improved.There was significant difference between groups (P<0.05).Children with cough,wheezing,dyspnea,wheezing disappearance time and hospitalization time of observation group were (3.26±0.71),(2.19±0.85),(3.82±0.67),(4.27±0.96),(5.74±1.06)d compared with the control group was significantly reduced.The difference between the two groups was significant (P<0.05).There was no significant difference in the indexes of pulmonary function between the two groups (P>0.05).Compared with before treatment and the control group,FEV1,FVC,PEF after treatment of the observation group were(2.76±0.38)L,(3.07±0.56)L,(3.46±0.51)L·s-1,which was significantly increased (P<0.05). Conclusion Asarone injection combined with doxofylline for acute attack of bronchial asthma in children has obvious curative effect,which can quickly and effectively improve the symptoms and signs of children,shorten the length of hospital stay,and is worth reference and application.
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