| 彭鹏,葛圣林,张成鑫.冠状动脉周围心外膜脂肪厚度及CT值与冠心病的相关性研究[J].安徽医药,2018,22(9):1710-1713. |
| 冠状动脉周围心外膜脂肪厚度及CT值与冠心病的相关性研究 |
| Relationship between pericoronary epicardial adipose tissue thickness and CT value with coronary atherosclerotic heart disease |
| 投稿时间：2017-10-26 |
| DOI： |
| 中文关键词: 心外膜脂肪 冠状动脉粥样硬化性心脏病 冠状动脉CT血管造影 冠状动脉造影 |
| 英文关键词: Epicardial adipose tissue Coronary atherosclerotic heart disease CT angiography of coronary artery Coronary angiography |
| 基金项目: |
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| 中文摘要: |
| 目的 评价心外膜脂肪(EAT)厚度及CT值与冠心病的相关性。方法 入选行冠状动脉CT血管造影(CTA)检查的患者151例,其中经冠状动脉造影检查确诊为冠心病者81例,纳入冠心病组,正常者70例,纳入正常冠状动脉组。回顾冠状动脉CTA影像资料,测量冠状动脉周围EAT厚度及CT值。对冠心病患者造影结果进行SYNTAX评分,据此将所有冠心病患者分为两组:低积分组(SYNTAX评分≤32分),高积分组(SYNTAX评分＞32分)。分析EAT厚度及CT值与冠心病的相关性。结果 正常冠状动脉组EAT厚度低于冠心病组(P=0.007),CT值高于冠心病组(P=0.003)。冠心病患者中,低积分组EAT厚度低于高积分组(P=0.009),CT值高于高积分组 (P=0.007),经Person相关分析显示,EAT厚度与SYNTAX评分显著正相关(r=0.857,P<0.01),CT值与SYNTAX评分显著负相关(r=-0.835,P＜0.01),经logistic回归分析,EAT厚度及CT值与冠心病具有独立相关性。结论 EAT厚度及CT值与冠心病及SYNTAX评分具有显著相关性,对冠心病诊断及病变程度具有潜在预测价值。 |
| 英文摘要: |
| Objective To evaluate the relationship between thickness and CT value of pericoronary epicardial adipose tissue (EAT) with existence and severity of coronary atherosclerotic heart disease.Metheod A total of 151 patients examined by CT angiography of coronary artery were enrolled.81 cases of patients were diagnosed with coronary heart disease according to Coronary angiography,embedded in coronary heart disease group.The other 70 patients were embedded in normal coronary artery group.Pericoronary EAT thickness and CT value were measured by reviewing medical images retrospectively.Syntax scores were calculated to evaluated severity of coronary lesions.And we divided all coronary heart disease patients into 2 groups according to SYNTAX scores:low score group(≤32 score) and high score group(＞32 score). Result Mean thickness of normal group was less than CAD group (P=0.007).CT value of nomal group was higher than CAD group (P=0.003).Mean thickness of low score group was lower than high score group (P=0.009),CT value of low score group was higher than high score group (P=0.007).Pearson correlation analysis presents that EAT thickness was significantly correlated with SYNTAX score(r=0.857,P<0.01),and CT value was significantly negatively correlated with the SYNTAX score(r=-0.835,P<0.01).Multiple Logistic regression analysis presents that thickness and CT value were independent to coronary heart disease.Conclusion EAT thickness and CT value demonstrate a significant correlation with existence of SYNTAX scores and coronary artery stenosis,which has potential predictive value for coronary heart disease. |
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